AAS and muscle repair

[anabolictonic]

What aas aids tissue repair the greatest.. or are they all about equal?

[anabolictonic]

bump

[azz10]

gd question bro.. i'm curious to know too given me strained hammy..

[MuscleScience]

Testosterone probably would be the standard. Other AAS are used for muscle wasting, burn victims ect....

[azz10]

Testosterone probably would be the standard. Other AAS are used for muscle wasting, burn victims ect....

thanxs for e info musclescience.. does that means recovery time from muscle strained will be sped up with test use?

[MuscleScience]

Possible, AAS increase protein synthesis. It basically helps your body recover after a workout. That more than anything is its main effect on skeletal muscle.

[azz10]

great info mate.. with the increased protein synthesis from AAS, does that mean we gotta increase our usual protein intake to facilitate the recovery? or can protein intake remain the same..

[MuscleScience]

great info mate.. with the increased protein synthesis from AAS, does that mean we gotta increase our usual protein intake to facilitate the recovery? or can protein intake remain the same..

Well thats a complicated question but I will put it to you like this. A person only needs about 50 grams of protein a day to maintain body mass. If a person wants to gain muscle mass of course protein intake needs to be increased.

One process that AAS really helps is amino acid recycling. This is the normal breakdown of proteins into their amino acids complement such as signal proteins, regulator proteins, structural proteins and enzymes. These Amino Acids are recycled fairly efficiently, one of the proposed theories out there is that AAS will cause the body to react and be more efficient at this process.

That means in theory a person can take AAS and not have to increase Protein intake to gain mass to a certain extent. How much mass will you gain on normal feeding, that I have no idea.

To add some complexity AAS also helps increase the assimilation of all nutrients. This means that the body will absorb and convert more of the energy stored in food as usable work. This effect is highlighted in cattle that are implanted with Tren pellets. The same mechanism is believed to me in humans as well.

[FireGuy]

Here is some good info on the subject, yes, it's copy and paste job.

"How to Increase Collagen Synthesis

Originally posted by AnimalMass on competitivemuscle.com

While injecting test increases protein syntesis by roughly 50 times, depending on dose and time, most bodybuilders forget that it will reduce collagen synthesis by more than 50% -- more like 80%, giving you the collagen synthesis rate of a senior citizen. Since collagen makes up tendons, bros are very prone to injury if they continue to lift very heavy, unless they cycle off T and let their collagen synthesis get back to normal. It's like having the skeletal muscle of a gorilla with the tendons of a very old man.

Winstrol increases collagen synthesis. It will give you bigger tendons. However, your body compensates for this by making them more brittle, weaker, and more prone to injury. I can't tell you how many bros work out anaerobically and become injured while on winstrol. Guys who lift in the 1-5 rep range while on winstrol, to baseball players who sprint all out from a stationary position -- winstrol should be the LAST drug they choose. Most of them like winstrol because they don't get the weight gain from it but it is very detrimental to bros who train for any sport anaerobically. Tendons tear easily on it.

Also, the drugs I mention increase collagen syn while also increasing collagen cross-linking integrity, making for a much stronger tendon.

Winstrol, on the other hand, will dramatically increase collagen syn, but ironically it decreases collagen cross-linking integrity, thus making a much weaker tendon.

You can plan a cycle of AAS which will increase collagen synthesis and skeletal muscle growth at the same time. The key is the drug(s) you choose.

Deca , Equipoise , Anavar , and Primobolan will ALL increase skeletal muscle while at the same time dramatically increase collagen syn and bone mass and density, leaving you with a substantially reduced chance of becoming injured than if you choose to use AAS like sus, cyp, or enth.

While testosterone will increase bone mass and density, even at supra-physiological levels, the result is weaker tendons due to inhibition of collagen syn.

To plan a cycle where the goal is to increase skeletal muscle mass/strength while at the same time increase joint/tendon/ligament strength, enough to keep up with the dramatic increase in skeletal muscle, you must choose drugs like Eq, Deca, Anavar, or Primo as the base of your cycle. Testosterone and its esters can be added to your cycle to keep levels within a 'normal' physiological range (ie, 100-200 mg/wk) but must not go above this. Since drugs like eq, deca, anavar and primo will reduce endogenous, natural levels of test, these levels may be maintained with exogenous test in the 100-200 mg/wk range. Test at this dose will not inhibit collagen syn, but paradoxically, will help increase it. It is when exogenous testosterone is used > 200 mg/wk that collagen syn is inhibited.

Deca @ 3 mg/kg a week(about 270 mg/wk for a 200 lb male) will increase procollagen III levels by 270% by week 2. Procollagen III is a primary indicator used to determine the rate of collagen syn. As you can see, deca is a very good drug at giving you everything you want -- an increase in collagen syn, an increase in skeletal muscle, and increases in bone mass and density. The one thing it does not give you is wood

Primobolan, @ 5 mg/kg, will increase collagen synthesis by roughly 180% -- less than deca and equipoise but still substantial.

Equipoise @ 3 mg/kg will increase procollagen III by approximately 340% -- slightly better than deca.

Oxandrolone has over a hundred studies documenting its effectiveness at treating patients needing rapid increases in collagen syn to enhance healing.

These drugs have longer half-lives than most other AAS, so this should be considered when timing your post cycle clomid use. Here they are:

Deca: 15 days Equipoise: 14 days Primobolan: 10.5 days

Anavar has a half-life of only 8 hours so it should not pose a problem.

GH is probably the most remarkable drug at increasing collagen synthesis. It increases collagen syn in a dose dependant manner -- the more you use, the more you will increase collagen syn. It has also demonstrated this ability in short and long term studies. From what I've read, hGH at 6 iu/day increased the collagen deposition rate by around 250% in damaged collagen structures. This result indicates that the increased biomechanical strength of wounds to collagen structures treated with biosynthetic human growth hormone was produced by an increased deposition of collagen in the collagen structures.

Eq, primo, anavar, and deca are all good -- they increase several biomakers of collagen syn -- ie, type III, II, I, procollagen markers. GH just seems to do so most dramatically.


It makes sense that since deca has been shown in many studies to promote collagen biosynthesis (although to my knoweledge mostly within the scope of degenerative diseases) in correlation with anecdotal experience of symptom alleviation in trained athletes that a conservative long term cycle of deca durabolin coupled with exercise targeted at rehabilitation rather than mass gains and nutrional support (collagen substrates such as col. hydrolysates, glucosamin msm etc.?) could have a theraputic effect on problematic connective tissue.

[meathead320]

I am not entirely convince that it is or ever was testosterone causing a drop in collagen synthesis. So far as I know nothing about its chemical action would make it weaken a tendon.

Interesting to me is that some steroids that cause connective tissues to strengthen, like EQ, and Deca as far as I know (and please point it out if I’m wrong) are estrogen (E2 Estradiol) mediated. Meaning some of the gains are caused by aromatizing into estrogen.

Estradiol I always thought was the builder of connective tissue strength and even bone strength.

Lots of guys notice when they use too much AI’s during a cycle the gains slow too.

My offhand theory on the whole test = weak tendons is a 2 part theory:

A). Dose dependant. Guys using 200mg EW on high end HRT will have steel cable tendons, while guys pushing a friggin 1 gram a week may be the guys with issues.

B). Quite very well an over use of SERMS and AI’s that either block Estradiol from taking its effects on the tendons, or drop E2 too low all together causing a drop in collagen.



In my instance, test without an AI actually makes my finger nails thicker and I feel far less pain. Then again, I am only on 200mg EW for HRT, and I rarely ever use AI’s.

[azz10]

u guys are a legend..thanxs for e helpful info.. but is there anything on tbol as well?

[LATS60]

great info mate.. with the increased protein synthesis from AAS, does that mean we gotta increase our usual protein intake to facilitate the recovery? or can protein intake remain the same..

Protein intake can remain the same, it's bcaa's that really help, i posted medical article on this some time ago.

[azz10]

LATS60.. can u direct me to ur article? cant seem to find it in the search..

does that mean that i can still maintain the same protein dosage but up the BCAA?

i'm not exactly looking at bulking up.. but just using AAS to assist in recovery and strength increase..