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  1. #1
    dece870717's Avatar
    dece870717 is offline Knowledgeable Member
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    Tren and Winstrol genotoxic and cytotoxic? So whats it mean to us?

    Found a study about it here...

    http://www.aensi.org/aeb/2007/39-43.pdf

    Conclusion taken from study....

    "The outcome of this investigative experiment
    shows that stanozolol and trenbolone have the
    potential to be genotoxic and cytotoxic, especially at
    40 and 60 mM, with or without metabolic activation,
    in cultured human lymphocytes. The evaluation of
    these genotoxicity tests is a useful tool for
    determining the toxic effects of potentially genotoxic
    chemicals, leading to identification of such
    carcinogenic agents. It is advisable to use the steroids
    studied here at their lowest effective dosage so that
    the risk to public health could be minimized. The
    risk of damage to human genetic material is very
    likely at higher doses of these drugs."

    Read it today and don't know what to think of it, especially with that last sentence.

  2. #2
    LATS60's Avatar
    LATS60 is offline Anabolic Member
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    Quote Originally Posted by dece870717 View Post
    Found a study about it here...

    http://www.aensi.org/aeb/2007/39-43.pdf

    Conclusion taken from study....

    "The outcome of this investigative experiment
    shows that stanozolol and trenbolone have the
    potential to be genotoxic and cytotoxic, especially at
    40 and 60 mM, with or without metabolic activation,
    in cultured human lymphocytes. The evaluation of
    these genotoxicity tests is a useful tool for
    determining the toxic effects of potentially genotoxic
    chemicals, leading to identification of such
    carcinogenic agents. It is advisable to use the steroids
    studied here at their lowest effective dosage so that
    the risk to public health could be minimized. The
    risk of damage to human genetic material is very
    likely at higher doses of these drugs."

    Read it today and don't know what to think of it, especially with that last sentence.
    Have the potential, thats the key phrase here.
    Cigarettes have the potential to cause lung cancer.
    Alcohol has the potential to cause liver damage.
    Take it with a pinch of salt and forget it.

  3. #3
    WARMachine's Avatar
    WARMachine is offline Post Cycle Extraordinaire~GOT PCT?
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    I gotta agree with Lats...

    This seems like more of the same thing we see ED on CNN and FOX News.

    Like Romano says, "Show me the bodys!"

  4. #4
    crispybacon is offline Junior Member
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    Genotoxic would be damage to DNA or other genetic info, cytotoxic would be in regard to cellular toxicity/damage.

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