T3 : Once a Day or Split Dose ?

[davpet]

The package insert for Cytomel (T3) says that the half-life for T3 is 2.5 days and that it should be taken all at once.

Bodybuilding sites say that the half-life of T3 is 10 hours and that your dose should be split through out the day.

Who should you believe ?

[LATS60]

The package insert for Cytomel (T3) says that the half-life for T3 is 2.5 days and that it should be taken all at once.

Bodybuilding sites say that the half-life of T3 is 10 hours and that your dose should be split through out the day.

Who should you believe ?

Start off low and increase the dose slowly, 25mcg is a good starting point, as you start taking more tabs split them into three regular doses.

[davpet]

Start off low and increase the dose slowly, 25mcg is a good starting point, as you start taking more tabs split them into three regular doses.

...but if the half-life really is 2.5 days, it won't make a difference if you took it all at once or split it up.

Does splitting it up decrease the risk of side-effects (heart palpitations, anxiety etc) ?

[LATS60]

...but if the half-life really is 2.5 days, it won't make a difference if you took it all at once or split it up.

Does splitting it up decrease the risk of side-effects (heart palpitations, anxiety etc) ?

LOL, i didn't post that for fun mate, i was just answering your Q, you certainly don't have too take my advice, i was just offering it.

[johnnybigguns]

I split mine up over the day

[bmit]

always read to split it up and in my practice that seems to cut down on sides like heart racing

[JiGGaMaN]

The package insert for Cytomel (T3) says that the half-life for T3 is 2.5 days and that it should be taken all at once.

Bodybuilding sites say that the half-life of T3 is 10 hours and that your dose should be split through out the day.

Who should you believe ?

well, obviously i would believe the pharmaceutical company. But heres where things differ:
Cytomel is for hypothyroidism, taken once a day because the dosage is only 25mcg. The dosing protocol for it probably says once a day because its similar to how the body produces T3.

The bodybuilding sites recommend spreading out the dosage because the amount consumed is generally not and HRT dose, but rather to increase metabolism to supraphysiological levels (which can be very dangerous). In an attempt to prevent a super high peak plasma level, such as one would experience if they took everything at once, the authors suggest spreading it out. That way you get a stable blood level rather than the 'roller-coaster' effect. Its safer to do it that way, but then again, high dosages of T3 arent really safe to begin with.