reason for early fusing of bones?

[Jumbo18]

what is the reason for early fusing of the ends of your epiphyseal bones? is it because the muscle mass increasing too quick?

[Phate]

what is the reason for early fusing of the ends of your epiphyseal bones? is it because the muscle mass increasing too quick?

no, AS change your endocrine system and in maturing adults this disruption can stop maturity(puberty) from continuing

[Jumbo18]

ohh i see, i remember reading a long time ago someone posted somewhere saying it was due to the increase in estrogen, but i always thought that didn't make sense to me. well thanks.

[Immortal Soldier]

In conclusion, our data suggest the following new model. (i) The growth plate undergoes programmed senescence including a decline in growth rate, proliferation rate, and the number and size of chondrocytes. This program may be due to replicative senescence of the growth plate chondrocytes. (ii) Epiphyseal fusion is a rapid process that is triggered when the senescence program reaches a critical point. Specifically, epiphyseal fusion seems to be triggered when the proliferative potential of the growth plate chondrocytes is finally exhausted. (iii) Estrogen accelerates the growth plate senescence program, thereby exhausting the proliferative potential of growth plate chondrocytes sooner, consequently triggering earlier epiphyseal fusion. This model may also apply to humans, providing an explanation for certain clinical observations: the catch-down growth in children following estrogen exposure, the prolonged and age-dependent delay between the onset of estrogen and the onset of fusion, and the acceleration of bone age by estrogen.

http://www.pubmedcentral.nih.gov/art...gi?artid=34445

[Jumbo18]

so i did a deca only cycle when i was 20, just speaking in terms for early fusing. will the deca only affect closing my growth plates sooner or not because it doesn't aromatise and not much estrogen increase?