Reversitol? Thoughts?

[BigJuice777]

Does anyone have any opinions on Reversitol as a PCT? A buddy has been lifting for 10+ years, seems to know his stuff, and he swears by it... I am just looking for a few second opinions. It's hard to imagine an OTC can be just as good as prescription grade.

Thanks in advance!!

Sorry... Probably should have put this in the PCT forum. My apologies.

[steroidsarebad]

I have seen people recover from PH cycles with Resveratrol products (with blood work) but a long test cycle is a whole different ballgame. I have never seen blood work for that. Most likely the people who would use an otc product for pct for steroids are the same people who wouldn't get their blood tested.

[40plusnewbie]

I have no opinion of it as a pct drug but I did see a medical show on it where they administered mega doses to some mice and to others none. The made the mice real fat and the ones on resveratrol could run faster and longer than the others. Also, when they cut them open the non resveratol rats had fat organs and the ones on resveratol had normal, healthy organs. The dr's who were studing this stuff were very enthusiastic about it. But it was being administered in mega doses, like the ammt u would get in 10,000 bottles of wine for each dose.

I think it holds promise as some sort of anti-aging drug in the future, then again I'm often wrong.

[matt77]

Does anyone have any opinions on Reversitol as a PCT? A buddy has been lifting for 10+ years, seems to know his stuff, and he swears by it... I am just looking for a few second opinions. It's hard to imagine an OTC can be just as good as prescription grade.

Thanks in advance!!

Sorry... Probably should have put this in the PCT forum. My apologies.

Well the new version Iforce has out now is crap. It used to be used for a mild PH cycle but I would not even consider it for anything anymore.

I have seen people recover from PH cycles with Resveratrol products (with blood work) but a long test cycle is a whole different ballgame. I have never seen blood work for that. Most likely the people who would use an otc product for pct for steroids are the same people who wouldn't get their blood tested.

I have no opinion of it as a pct drug but I did see a medical show on it where they administered mega doses to some mice and to others none. The made the mice real fat and the ones on resveratrol could run faster and longer than the others. Also, when they cut them open the non resveratol rats had fat organs and the ones on resveratol had normal, healthy organs. The dr's who were studing this stuff were very enthusiastic about it. But it was being administered in mega doses, like the ammt u would get in 10,000 bottles of wine for each dose.



I think it holds promise as some sort of anti-aging drug in the future, then again I'm often wrong.

Guys its a common mistake talking about Iforce's Reversitol but its not Resverstrol from grapes/wine. He's talking about a formula Iforce has thats a Test booster.

[steroidsarebad]

Well the new version Iforce has out now is crap. It used to be used for a mild PH cycle but I would not even consider it for anything anymore.


Guys its a common mistake talking about Iforce's Reversitol but its not Resverstrol from grapes/wine. He's talking about a formula Iforce has thats a Test booster.

Reversitol's main selling point is the fact that it acts like a SERM because it contains trans-resveratrol which makes it "desirable" for pct

[mlb29]

ATD and 6 bromo and indole-3-carbinol r the best thing in that for pct. for a mild prohormone cycle .

[matt77]

Reversitol's main selling point is the fact that it acts like a SERM because it contains trans-resveratrol which makes it "desirable" for pct

Well that maybe their selling point but the things mlb put is what works like a pct. I would still not depend on it for PCT when AR-R products are so easy to come by.

ATD and 6 bromo and indole-3-carbinol r the best thing in that for pct. for a mild prohormone cycle .

Agree 100%

[magic32]

From what I've read it's touted as an anti-oxidant loaded, cholesterol lowering, circulation improving supplement. From the literature I've read, I put little faith in the latter claims and would not consider it impactful during PCT, but the former/anti-oxidant claim appears sound.

[Bonaparte]

Like Matt77 said, Reversitol V2 is crap, since they had to remove the useful steroidal AIs. Either way, OTC products don't really do shit for PCT, as they are only seemingly successful at bouncing guys back after mild cycles...ones that they would have recovered from naturally just the same. Get a SERM.

[Bryan2]

It does nothing for raising your test levels.

However it is an amazing antioxidant, only problem with it is it is VERY hard to absorb orally. I have seen some products that are altered to improve oral availability but I cant comment on if it works or not


The reason the ingredients to what was posted above worked was that it contained AIs which block the conversion to estrogen, thus the body makes more test levels.

[BigJuice777]

Thanks guys... that is what I figured. If it was SO great, this board would be talking about reversitol instead of the proven Nolva, Clomid, etc. I just wanted to get a few other opinions. It didn't make sense to me that an OTC could be as effective as prescription grade. Kinda like 'herbal' juice compared to AAS... it might work, but there is no substitute for the real thing.

Thanks for the opinions.

[Swifto]

Apart from its anti-oxidant benefits, the rest aren't good.

Ok, it may be a natural SERM and reduce E2, but as stated above it absorption rate it low.

Its also an anti-androgen, so adding it in PCT or on cycle is far from optimal.



Repressive Effects of Resveratrol on Androgen Receptor Transcriptional Activity


Wen-feng Shi1#, Melanie Leong2#, Ellen Cho2, Joseph Farrell2, Han-chun Chen3, Jun Tian1, Dianzheng Zhang2,3*
1 Department of Blood Purification, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China, 2 Department of Biochemistry and Molecular Biology and Center for Chronic Disorders of Aging, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, United States of America, 3 Department of Biochemistry, School of Biological Science and Technology, Central South University, Changsha, Hunan, People's Republic of China

Abstract Top

Background
The chemopreventive effects of resveratrol (RSV) on prostate cancer have been well established; the androgen receptor (AR) plays pivotal roles in prostatic tumorigenesis. However, the exact underlying molecular mechanisms about the effects of RSV on AR have not been fully elucidated. A model system is needed to determine whether and how RSV represses AR transcriptional activity.

Methodology
The AR cDNA was first cloned into the retroviral vector pOZ-N and then integrated into the genome of AR-negative HeLa cells to generate the AR(+) cells. The constitutively expressed AR was characterized by monitoring hormone-stimulated nuclear translocation, DNA binding, and transcriptional activation, with the AR(-) cells serving as controls. AR(+) cells were treated with RSV, and both AR protein levels and AR transcriptional activity were measured simultaneously. Chromatin immunoprecipitation (ChIP) assays were used to detect the effects of RSV on the recruitment of AR to its cognate element (ARE).

Results
AR in the AR (+) stable cell line functions in a manner similar to that of endogenously expressed AR. Using this model system we clearly demonstrated that RSV represses AR transcriptional activity independently of any effects on AR protein levels. However, neither the hormone-mediated nucleus translocation nor the AR/ARE interaction was affected by RSV treatment.

Conclusion
We demonstrated unambiguously that RSV regulates AR target gene expression, at least in part, by repressing AR transcriptional activity. Repressive effects of RSV on AR activity result from mechanisms other than the affects of AR nuclear translocation or DNA binding.

Citation: Shi W-f, Leong M, Cho E, Farrell J, Chen H-c, et al. (2009) Repressive Effects of Resveratrol