diphenhydramine aka. benadryl does not work to prevent tachyphylaxis caused by significant dosages of clenbuteral continuously. diphenhydramine does not stabilize or re-sensitize the beta-2 adrenergic receptors directly or indirectly. the bronchial beta-2 adrenergic receptors are the receptors that clenbuteral selectively targets for its effect.
in my research i have used clenbuteral 4 times. I am familiar with its effect and when its effect begins to diminish. on the 3rd time I supplemented 50mg of dyphenhydramine as a test to see if it had any effect and it did not work. i began to have diminishing effects dosing clenbuteral @120mcg after 9 consecutive days and at which point I began to supplement the 50mg of dyphenhydramine in conjunction with the clenbuteral and was completely desensitized to its effect by day 13.
if you are looking to keep clenbuteral working optimally and prevent tachyphylaxis to run significant doses continuously longer then 10days then ketotifen will work.
diphenhydramine(benadryl) will not work
50mg of dyphenhydramine will leave you completely stupefied...other than that its does two things in conjunction with clenbuteral
1. jack
2. shit
i know its in the pages of everybody's favorite book. but i believe the author either didn't have any personal experience with the compound or made a mistake in his research or both. it was an interesting theory but benadryl does not work in the manner in which is presented in that explanation