I am considering injecting actovegin 5ml prior to workout while on cycle. Has anyone ever used actovegin and what was your experience with it?
Here's a description:
How does the medication works?
Actovegin ® is a hemoderivative which is produced by dialysis and ultrafiltration (the molecular weight for compounds is less than 500 daltons). Actovegin works by increasing the utilization of glucose, oxygen (increases the resistance to hypoxia), enhances energetic metabolism. All of this in general results in strengthening of energetic state of the cells (especially in case of oxygen deficit). Initially, extracellular glucose enters the cell through the appropriate transport mechanisms, after that glucose is metabolized. Products of glucose break down participate in the citric acids cycle. In results of this cycle some important amino acids are produced such as glutamate and aspartate. Numerous experiments have shown that inositol oligosacharides are able to regulate some of the insulin-dependent enzymes, such as cAMP-phosphodiesterases, adenylate cyclase, and pyruvate dehydrogenase. inositol oligosaccharides fraction of Activegin activates pyruvate dehydrogenase and thus increases glucose utilization.
Actovegin ® also stimulates oxygen consumption. This leads to the stabilization of the cells plasma membrane during ischemia and reduces the formation of lactate.
The medication increases the intracellular levels of glucose, improves oxidative metabolism, thus improving energy balance and deposit, the amount of ATP, ADP, glutamate, aspartate and GABA in increased as well. In cerebrovascular disorders (for example in patients with dementia), the transport of glucose through the blood-brain barriers and it utilization is significantly decreases. At the same time the activity of pyruvate dehydrogenase and acetylcholine concentration are reduced as well. The preparation Actovegin acts directly on glucose mechanisms of utilization and the condition of patients is gradually improving. The medication possesses its therapeutic effects also in peripheral (arterial and venous) blood disorders and their complications (arterial angiopathy, ulcerous damage of the lower extremities). The drug is actively used to speed up to process of wounds and burns healing.