Tren article

[lemonada9]

17β-Hydroxyestra-4,9,11-trien-3-one (trenbolone ) exhibits tissue selective anabolic activity: effects on muscle, bone, adiposity, hemoglobin, and prostate


basically says a lower dose keeps prostate same, while having myotropic effects :P

Abstract
Selective androgen receptor modulators (SARMs ) now under development can protect against muscle and bone loss without causing prostate growth or polycythemia. 17β-Hydroxyestra-4,9,11-trien-3-one (trenbolone), a potent testosterone analog, may have SARM-like actions because, unlike testosterone, trenbolone does not undergo tissue-specific 5α-reduction to form more potent androgens. We tested the hypothesis that trenbolone-enanthate (TREN ) might prevent orchiectomy-induced losses in muscle and bone and visceral fat accumulation without increasing prostate mass or resulting in adverse hemoglobin elevations. Male F344 rats aged 3 mo underwent orchiectomy or remained intact and were administered graded doses of TREN, supraphysiological testosterone-enanthate, or vehicle for 29 days. In both intact and orchiectomized animals, all TREN doses and supraphysiological testosterone-enanthate augmented androgen-sensitive levator ani/bulbocavernosus muscle mass by 35–40% above shams (P ≤ 0.001) and produced a dose-dependent partial protection against orchiectomy-induced total and trabecular bone mineral density losses (P < 0.05) and visceral fat accumulation (P < 0.05). The lowest doses of TREN successfully maintained prostate mass and hemoglobin concentrations at sham levels in both intact and orchiectomized animals, whereas supraphysiological testosterone-enanthate and high-dose TREN elevated prostate mass by 84 and 68%, respectively (P < 0.01). In summary, low-dose administration of the non-5α-reducible androgen TREN maintains prostate mass and hemoglobin concentrations near the level of shams while producing potent myotrophic actions in skeletal muscle and partial protection against orchiectomy-induced bone loss and visceral fat accumulation. Our findings indicate that TREN has advantages over supraphysiological testosterone and supports the need for future preclinical studies examining the viability of TREN as an option for androgen replacement therapy.

[Blade15]

Nice Info...

[m3rk11]

gonna start first cycle of tren and im stokeed!

[lovbyts]

What do they consider a LOW dose and are they suggesting NO test? hmmm Ill pass

[Turkish Juicer]

What the hell is a ''low dose''? One has to specify dosage in any scientific cstudy.

Scientists who conducted that study should be given Tren without Test and see what happens to their endocrine system in a couple of weeks.

Now, that would be an article I would like to read...

[lemonada9]

in the study they actually did use Test e along with the tren for one of the subjects.