nandrole androgenic causing genotoxic and castrogenic effects

[kluska399]

Just got this app on my droid@ alled Steroids. The picture is a skull and crossbones lol. But I just read this article in it that nandrolone androgenic hormone was distributed to lab rats in an 8 month study and they suffered genotixic and castrogenic adverse effects resulting in cancer. Can't find it ANYWHERE online and can't copy and paste from the article. Might type it later...

Anyone else see this or have opinions?

[dece870717]

Is it this?

http://www.ncbi.nlm.nih.gov/pubmed/21717486

Abstract

Nandrolone is an androgenic-anabolic steroid (AAS) with diverse medical applications but taken indiscriminately by some to rapidly increase muscle mass. The aim of this study was to evaluate the genotoxic and clastogenic potential of nandrolone (deca-durabolin®) in vivo in different cells of mice, using the comet assay and micronucleus test, respectively. The animals received subcutaneous injection of the three doses of the steroid (1.0, 2.5 and 5.0 mg kg(-1) body weight). Cytotoxicity was assessed by scoring 200 consecutive total polychromatic (PCE) and normochromatic (NCE) erythrocytes (PCE-NCE ratio). The results showed a significant dose-related increase in the frequency of DNA damage in leukocytes, liver, bone marrow, brain and testicle cells at the three tested doses and a significant increase of the micronucleated polychromatic erythrocytes at all tested doses. Under our experimental conditions, the nandrolone steroid hormone showed genotoxic and clastogenic effects when administered subcutaneously to mice. Copyright © 2011 John Wiley & Sons, Ltd.