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10-07-2011, 01:18 AM #1Junior Member
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arimidex and aromasin? should i run both For first cycle
Hey i was wondering i have read mixed reviews so thought i would ask you guys. This is my first cycle so dont no if my gyno prone but i was a bit large few years ago so i have a bit of fat tissue around my nipples that is a bitch to get rid of so i think i will def run A-Dex throught my cycle at .5mg E3D (increase if more gyno symptoms come) . The question i was wondering is for my PCT i am running Nolva for 4 weeks, but i was also going to run aromasin aswell here is my post cycle.
Post Cycle
Week Nolvadex
1 40mgs/day
2 20mgs/day
3 10mgs/day
4 10mgs/day
Week Aromasin
1 20mgs/day
2 20mgs/day
3 10mgs/day
Its only for a simple Test e 500 a week cycle as its my first. but i was wondering both a-Dex and aromasin or jsut A-dex and nolva only PCT?
Stats before use ask lol
Age 26 and 10 months
Weight 91 kg
Height 179 cm
Bf 14 - 15 %
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10-07-2011, 05:24 AM #2Junior Member
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10-07-2011, 06:13 AM #3Recognized Member Winner - $100
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Aromasin Warnings & Precautions
WARNINGS
Included as part of the PRECAUTIONS section.
PRECAUTIONS
Administration with Estrogen-Containing Agents
AROMASIN (exemestane) should not be coadministered with estrogen-containing agents as these could interfere with its pharmacologic action.
DRUG INTERACTIONS
Tamoxifen
Co-administration of anastrozole and tamoxifen in breast cancer patients reduced anastrozole plasma concentration by 27%. However, the coadministration of anastrozole and tamoxifen did not affect the pharmacokinetics of tamoxifen or N-desmethyltamoxifen. At a median follow-up of 33 months, the combination of ARIMIDEX (anastrozole) and tamoxifen did not demonstrate any efficacy benefit when compared with tamoxifen in all patients as well as in the hormone receptor-positive subpopulation. This treatment arm was discontinued from the trial. [see Clinical Studies]. Based on clinical and pharmacokinetic results from the ATAC trial, tamoxifen should not be administered with anastrozole.
Estrogen
Estrogen-containing therapies should not be used with ARIMIDEX (anastrozole) as they may diminish its pharmacological action.Last edited by MR10X; 10-07-2011 at 06:16 AM.
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10-07-2011, 06:35 AM #4Junior Member
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?? From what I gather are u saying nolva by itself had the Same results as a-dex and nolva?? I was gonna run the a-dex before the nolva not at the same time and not for 33 months lol
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10-07-2011, 09:00 AM #5Recognized Member Winner - $100
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Arimidex and Nolvadex do 2 entirely differnt things,Arimidex inhibits estrogen conversion and Nolvadex ties up the estrogen receptor so estrogen cant bind to it and cause gyno.Estrogen is what makes womens tits grow when they go through puberty,it will also make a mans tits grow also when he has too much.This info is from the manufacturer and are trials where they test the drugs and effects,it is the drug manufacturers literature that is supplied with the drug. what they are saying is Nolvadex lowered the arimidex blood level 27%,i suppose you could increase the dosage of arimidex to get a higher level which is not reliable without blood test to see what your Estrogen actually are. Airmidex did not effect the blood level of Nolvadex. If you use arimidex while on cycle and keep your estrogen level low or normal you shouldnt need Nolvadex. Use Nolvadex and Clomid for PCT and drop the Arimidex. The Nolvadex and clomid will increase your test level and LH level which is what you need for PCT.
Last edited by MR10X; 10-07-2011 at 09:03 AM.
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10-07-2011, 05:16 PM #6
If you're worried about gyno take small doses of aromasin throughout cycle. eod or e3d. 12.5 should be cool. Save the nolva for PCT.
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10-07-2011, 05:34 PM #7
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10-07-2011, 07:15 PM #8Junior Member
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So are u saying just run nolva and clomid for my pct and not run an ai??
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10-07-2011, 07:17 PM #9Junior Member
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Cb714 i was planning on takin a dex during cycle den aromasin and nolva pct as i read that they work better together for a pct
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10-07-2011, 07:43 PM #10
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10-08-2011, 03:53 AM #11Junior Member
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So no aromasin with nolva I heard they were good together or us there no point having 2 AIs in a simple test cycle
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10-08-2011, 12:50 PM #12
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10-08-2011, 02:36 PM #13Recognized Member Winner - $100
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Nolvadex is not and AI its a Serm.You can use one or the other for PCT but using Nolvadex lowers Airmidex's level by 27%.A doctor that specializes in Recovery told me he prefers a Serm over an AI for recovery.
DRUG INTERACTIONS
Tamoxifen
Co-administration of anastrozole and tamoxifen in breast cancer patients reduced anastrozole plasma concentration by 27%. However, the coadministration of anastrozole and tamoxifen did not affect the pharmacokinetics of tamoxifen or N-desmethyltamoxifen.
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