new study on boldenone

[aldric]

http://www.ncbi.nlm.nih.gov/pubmed/21878449

So what do you guys think about this new study?

These findings suggest that misuse of the boldenone undecylenate may contribute to the occurrence of a chronic renal injury that may lead to a progressive renal failure.

[aldric]

http://www.ncbi.nlm.nih.gov/pubmed/20980358

A case study stating basicaly the same thing.

[im83931]

I've never been a fan of eq anyway.

[MR10X]

I have been using it for 30 years and my guts are just fine.............

[aldric]

I have been using it for 30 years and my guts are just fine.............

They're talking about kidneys...

[aldric]

Most steroids are hepatotoxic. And while hepatocytes have a very high cell proliferation rate and thus the liver will regenerate (except in case of liver fibrosis), the kidney on the other hand WILL NOT.
That's why I take these findings so dead serious.

If some guys out there think only about muscular gains, having a kidney transplant and staying on cyclosporines for the rest of your earthy life will definitely make you lose every ounce of gains you had before and after steroids.

I consider this site the most well-documented and unbiased source on steroids on the internet. So yeah... I may be new on this forum, but I suggest including this source in the article about boldenone on steroid.com

And also... some people might say "Well I never read a scientific paper / case study on boldenone-induced renal failure in humans anywhere" Well... these lesions are chronic, they evolve in time... Most people won't link them to AAS use. And how many out there are ready to admit to AAS use, when they are on the kidney-transplant waiting list. What insurance company would subsidize such a medical procedure if the patient "did it to himself"? I for one wouldnt' say anything about my AAS use if God-forbid I would be put in that situation.

[MR10X]

They're talking about kidneys...

I am too,everything is working just great even my testicals.,,,,,

[Bonaparte]

I am too,everything is working just great even my testicals.,,,,,

Yet "guts" refers to the digestive system, not every internal organ.

[MR10X]

Yet "guts" refers to the digestive system, not every internal organ.

The point is i am your long term study in steroid use and i dont have any issues with reguards to steroid use. I have done over 30 cycles off and on since 1980. A lot of decca and a lot of EQ,more recently i have done 4 cycles with Tren.....

[nutrition7771]

yea and my grandad smoked 60 a day for 40 years and he is fit as a fiddle at the age of 88, everyones different with drugs some will get away with it some wont.

[magic32]

I found the study interesting, thanks Aldric.
It's hard to dismiss the near incremental increases in glomerular lesions evidenced by the advancing scores:

"The glomerulosclerosis scores were 1.32 ± 0.10, 2.14 ± 0.11 and 3.02 ± 0.09 in groups 2, 3 and 4, respectively".

Of course the study doesn't mimic bb'er dosing of EQ, or cycling and therefore can't be equated with them...it's but interesting nonetheless.
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Actually the second study had quite different findings. It cited only suspicion of EQ use (likely because the guy got swole). Investigation of the suspicion revealed increased eGFR and creatinine levels, which although indicators, alone aren't enough to dictate disease as cited earlier in the passage, i.e. "...can lead to misdiagnosis of renal dysfunction." There was no actual renal disease, or even other hints at it:

"...in the absence of clinical signs, symptoms or other biochemical abnormalities of renal disease.
"

[MR10X]

[QUOTE=nutrition7771;5808110]yea and my grandad smoked 60 a day for 40 years and he is fit as a fiddle at the age of 88, everyones different with drugs some will get away with it some wont.[/QUOTE
Whats your point,i know young people know everything about everything there is to know about.............

[aldric]

I found the study interesting, thanks Aldric.
It's hard to dismiss the near incremental increases in glomerular lesions evidenced by the advancing scores:

Of course the study doesn't mimic bb'er dosing of EQ, or cycling and therefore can't be equated with them...it's but interesting nonetheless.
------------------------

Actually the second study had quite different findings. It cited only suspicion of EQ use (likely because the guy got swole). Investigation of the suspicion revealed increased eGFR and creatinine levels, which although indicators, alone aren't enough to dictate disease as cited earlier in the passage, i.e. "...can lead to misdiagnosis of renal dysfunction." There was no actual renal disease, or even other hints at it:

Hi there magic32

Actually the doses do mimic the ones that would be used by a bb. You are right about one thing. The study doesn't mimic the frequency of injections. Consider the fact the those cute little bunnies were injected with 5mg boldenone/kg body weight. That would be 400 mgs extrapolated in human dosage for a 80 kg male. And the fact that the frequency of AAS injections were lower and such renal lesions were induced only confirms that AAS users should be more careful with boldenone.

As for the second study which is a case study, the presence of boldenone was confirmed lab tests.
The guy had high creatinine levels but more important, an abnormal eGFR rate (eGRF = estimated glomerular filtration rate) which, once again, confirms that boldenone interacts in some way with renal function.