Dutasteride doubles the half-life of Oral T and TE
Quote:
Oral Testosterone in Oil Plus Dutasteride in Men: A Pharmacokinetic Study
Coadministration of D with oral T or TE significantly increased the 24-hr average serum T levels compared with administration of T or TE alone [average serum T after 400 mg dose, 8.7 ± 3.0 nmol/l (T) and 8.3 ± 5.7 nmol/l (TE) vs. 16.1 ± 5.8 nmol/l (T +D) and 15.0 ± 8.8 nmol/l (TE + D); P < 0.05 for T vs. T and D].
(The full text is easy to find, but I'm not allowed to post URLs yet)
Does anyone suspect that dutasteride may have this same effect on other oral steroids, like Var, or is there something special about oral T that makes this possible?