Cytomel (T3 - Liothyrine Sodium) and Test E...

[JohnnnyBlazzze]

I've been diggin around and search for some information regarding Cytomel. Almost all the threads I come across include running it with Clenbuterol and not to run Cytomel unless you are running AAS.

I have the understanding that Cytomel increases the nutrients into the mitochondria which would raise the metabolic rate in which the nutrients were burned. Which all in all would raise your metabolism and your bodies energy demands which will help burn fat due to increase in ATP.

I'm also discovering that T3 upregulates the beta 2 receptors in fat tissue...When your main goal is to burn fat this seems like something that would be counter-productive? Clen downregulates beta 2 receptors so is this the reason why they are ran together majority of the time and if so, Then would T3 not be effective ran alone? (Meaning alone by not running Clen, AAS still included.)

If one were to run T3 and Test E would you wait until about the 4/5th week for the Test to kick in before incorporating the T3 to avoid catabolism? I was curious if any members/vets had any experience with running Test E or any Test with Cytomel and not Clen and what there results/experiences were.

[Bonaparte]

I'm also discovering that T3 upregulates the beta 2 receptors in fat tissue...When your main goal is to burn fat this seems like something that would be counter-productive? Clen downregulates beta 2 receptors so is this the reason why they are ran together majority of the time and if so, Then would T3 not be effective ran alone? (Meaning alone by not running Clen, AAS still included.)

You have that backwards. Upregulation of Beta 2 would prime them for stimulation, meaning that you can burn more fat (if using a beta-2 agonist).
Clen activates Beta-2 receptors, which in turn downregulates them. But that is an unfortunate side effect of its actions, not its purpose.

[JohnnnyBlazzze]

You have that backwards. Upregulation of Beta 2 would prime them for stimulation, meaning that you can burn more fat (if using a beta-2 agonist).
Clen activates Beta-2 receptors, which in turn downregulates them. But that is an unfortunate side effect of its actions, not its purpose.

Great point, I guess my understanding of beta 2 receptors was off, thanks for the clarification.

[Schmooze]

And people thing most bodybuilders are meatheads. There's a lot of smarts on this forum. learning a lot, that's for sure.

[drose979]

What would be the optimal stack using T3? What about using it while on tren?

[austinite]

What would be the optimal stack using T3? What about using it while on tren?

Not on Tren alone. But if there is Test in that cycle, different story.

[drose979]

Not on Tren alone. But if there is Test in that cycle, different story.

Yea I would never run anything without test.

[austinite]

T3 wears me out. I get ridiculously tired and weak from as little as 50mcg. Wish it weren't the case.