Can the two of the above be tested in a uring test or just a blood test
cheers
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Can the two of the above be tested in a uring test or just a blood test
cheers
not sure mate. these are peptides, which are simple strings of amino acids. they have an incredibly short half life to boot.
Yes it can through urine, but unless your competing at next Olympics I doubt you will ever be tested, who is testing you?
Its very expensive and I assume they will only test winners at Olympics for this, the dose here is 10mg orally which has poor bioavailability, I seen something before about a dose of 500mcg injected IM also being detected, I'll see if I can find it, but if you took anything say 10-16 hrs even 20hr as in this study before testing then your fvcked
Determination of growth hormone releasing peptides (GHRP) and their major metabolites in human urine for doping controls by means of liquid chromatography mass spectrometry.
Thomas A, Höppner S, Geyer H, Schänzer W, Petrou M, Kwiatkowska D, Pokrywka A, Thevis M.
Source
Center for Preventive Doping Research/Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.
Abstract
A family of small peptides has reached the focus of doping controls representing a comparably new strategy for cheating sportsmen. These growth hormone releasing peptides (GHRP) are orally active and induce an increased production of endogenous growth hormone (GH). While the established test for exogenous GH fails, the misuse of these prohibited substances remains unrecognized. The present study provides data for the efficient extraction of a variety of known drug candidates (GHRP-1, GHRP-2, GHRP-4, GHRP-5, GHRP-6, alexamorelin, ipamorelin, and hexarelin) from human urine with subsequent mass spectrometric detection after liquid chromatographic separation. The used method potentially enables the retrospective evaluation of the acquired data for unknown metabolites by means of a non-targeted approach with high-resolution/high-accuracy full-scan mass spectrometry with additional higher collision energy dissociation experiments. This is of great importance due to the currently unknown metabolism of most of the targets and, thus, the method is focused on the intact peptidic drugs. Only the already characterised major metabolite of GHRP-2 (D-Ala-D-2-naphthylAla-L-Ala, as well as its stable isotope-labelled analogue) was synthesised and implemented in the detection assay. Method validation for qualitative purpose was performed with respect to specificity, precision (<20%), intermediate precision (<20%), recovery (47-95%), limit of detection (0.2-1 ng/mL), linearity, ion suppression and stability. Two stable isotope-labelled internal standards were used (deuterium-labelled GHRP-4 and GHRP-2 metabolite). The proof-of-principle was obtained by the analysis of excretion study urine samples obtained from a single oral administration of 10 mg of GHRP-2. Here, the known metabolite was detectable over 20 h after administration while the intact drug was not observed.
http://www.ncbi.nlm.nih.gov/pubmed/21298258
Like DanB said: unless you're an olympic athlete and you plan on taking it the day of testing, you're fine.
wont be winning the olympics.....im a pro rugby union player in the UK.....get tested by UK sport