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  1. #41
    Sworder is offline Banned
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    HCG is readily available to aromatase activity as well as the testosterone produced by it being subject to aromatase. I believe aromatase enzymes are in the SubQ fat and conversion to estrogen can happen there as well.I believe aromatase is the final step of the process regardless of the tissue it is expressed in. Sometimes it is incorrect to literally apply the aromastase inhibitor term to mean that it just inhibits aromatase :P Aromasin acts in a suicide fashion rather than inhibiting.

  2. #42
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    600@50 is offline Knowledgeable Member
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    Was this an E2 Sensitive test OP?

  3. #43
    Trying-Hard is offline Associate Member
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    Not sure what you mean by that, 600. If you look at the pic in my OP, you can see what kind of test it was.

  4. #44
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    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    He means that the sensitive assay is what is specific to males. Therefore you should use the sensitive assay for future tests. Kinda why I gave you that link above. Many TRT docs will say than anything else is pretty much invalid. If you use labcorp I can give you the proper codes codes so they don't screw it up. E2 is basically a subset of estrogen.

  5. #45
    Trying-Hard is offline Associate Member
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    Got ya. Thanks, kelkel

    I know you said that many TRT docs say anything other than E2 testing is "Invalid", but maybe you meant "innacurate"? I wouldn't *think* that estrogen testing is invalid given that it's probably an indicator of E2 levels.

    But anyway, I understand what you are saying and that sensetive E2 testing would be more accurate, which is what I should have gotten. So when I get BW in 3 weeks, I will get estrogen (to compare with my OP) and sensetive E2.

    Also, any ideas what the normal range is for E2? Thanks.
    Last edited by Trying-Hard; 10-02-2012 at 08:43 AM.

  6. #46
    Trying-Hard is offline Associate Member
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    Edit ^^^^

  7. #47
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    I wouldn't waste my money on another estrogen test. Just make sure you get an E2 Sensitive test because like Kel said that's the test males need and what data everyone here is used to working with. Don't panic on the other test results. Get the E2 Sensitive and post those numbers.

  8. #48
    Trying-Hard is offline Associate Member
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    Quote Originally Posted by 600@50 View Post
    I wouldn't waste my money on another estrogen test. Just make sure you get an E2 Sensitive test because like Kel said that's the test males need and what data everyone here is used to working with. Don't panic on the other test results. Get the E2 Sensitive and post those numbers.
    Thanks bro. Next I will be sure to get the sensitive estradiol assay as you and kelke mentionedl, but money aside, I may also get the estrogen as the OP for comparison sake.

    Any ideas what the normal range is for E2? In the meantime I will try to research it and see if I can come up with anything.
    Last edited by Trying-Hard; 10-02-2012 at 08:40 AM.

  9. #49
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    My last test was from Labcorp and for males they show 3-70 ng/ml. My E2 was 40 which is a little high but I felt fine. No itchy nips, good libido. I believe 20ish is what most shoot for.

  10. #50
    Trying-Hard is offline Associate Member
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    Ok, great. Thanks a lot, 600.

  11. #51
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    What 600 said. 20 to 30 is the recommended area per LEF. But it is subjective and should be based on how you feel, erection quality, etc.

    http://www.lef.org/magazine/mag2010/...ing-Men_01.htm

    kel

  12. #52
    Trying-Hard is offline Associate Member
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    Quote Originally Posted by kelkel View Post
    What 600 said. 20 to 30 is the recommended area per LEF. But it is subjective and should be based on how you feel, erection quality, etc.

    http://www.lef.org/magazine/mag2010/...ing-Men_01.htm

    kel
    Thanks so much, kelkel (and for the link). And now I understand why I can't keep an erection for more than 4 mins when having sex with my wife. Unbelievable!

    I am happy I am learning a lot, but I am frustrated I had to learn this way, lol. I thought I did all my research but I guess I didn't do enough. Although it is not a HUGE deal, I wish I can start all over again.

    Oh well, next time....=)

    THANK YOU!!
    Last edited by Trying-Hard; 10-02-2012 at 11:43 AM.

  13. #53
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    Quote Originally Posted by austinite View Post
    Watch the Titanic. If you cry, you're not taking enough.
    hahahah, i'll have to buy it. Who needs blood tests...just put titanic on your phone watch between sets

  14. #54
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    TH.......Don't be frustrated. All your research just keeps you from doing something really stupid. You'll continue to learn what works for you with each cycle you do. You'll get everything dialed in with bw and patience.

  15. #55
    Trying-Hard is offline Associate Member
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    Quote Originally Posted by 600@50 View Post
    TH.......Don't be frustrated. All your research just keeps you from doing something really stupid. You'll continue to learn what works for you with each cycle you do. You'll get everything dialed in with bw and patience.
    Appreciate the words of encouragement, 600. Thank you so much. It is a pleasure to have people like you, austinite, kelkel, etc around that educate the uneducated. =)

  16. #56
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    Shouldn't he be running an estradiol test not a total estrogen count?

    edit: i guess 600 covered it

  17. #57
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    Quote Originally Posted by Bonaparte View Post
    I disagree. If anything, it increases aromatase expression, which an AI will still take care of.
    The only way that an AI wouldn't work is if HCG converts directly to estrogen through some other means that the aromatase enzyme (which it cannot, since a peptide chain has a completely different structure than a sex hormone), or if it caused your adrenal glands to pump out an insane amount of estrogen. This is highly unlikely, since adrenal E2 production only accounts for maybe 2% of natural E2 levels in men.

    I haven't worried about this much lately, but I'm fairly certain the estrogenic effects of HCG are mainly due to it increasing Leydig cell activity in the testes, which is also where most E2 conversion takes place E2 is not produced by the testes, as you say, but by aromatase enzymes within the leydig cells of the testes).
    http://en.wikipedia.org/wiki/Estradi...e_reproduction

    Its not just leydig cells but also germ cells in various forms of differentation that also increase testicular estrogen levels. HCG can actually increase a fair whack from HCG. The testes account for around 15% of estrogen serum levels in males. Other extra-gondular sites of estrogen expression and synthesis are adipose tissue, the skin, brain (medial preoptic/anterior hypothalamus, the medial basal hypothalamus), adrenal glands, smooth muslce cells and finally bones (osteoblasts and possibly osteoclasts).

  18. #58
    Trying-Hard is offline Associate Member
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    I am getting blood work Monday. I am going through privatemdlabs.com. I don't see "sensitive estradiol", I just see "estradiol". Look here:

    http://www.privatemdlabs.com/lp/Estradiol.php

    Is this the correct test?

  19. #59
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    austinite is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~
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    ^ needs to be a sensitive E2 assay.

    http://www.privatemdlabs.com/lab_tes...4&search=#1001

  20. #60
    Trying-Hard is offline Associate Member
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    Thanks man!

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