Interested In taking clen when I start cutting. Is it catabolic if I take it by itself?
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Interested In taking clen when I start cutting. Is it catabolic if I take it by itself?
Are you running this alone or in combination with other agents? As long as your nutrition is designed properly, you shouldn't need to worry about being catabolic. Have you run clen before? Are you aware of the side effects?Quote:
Originally Posted by EarlyMuscles
no its actually thought to be anti-catabolic at higher doses...Quote:
Originally Posted by EarlyMuscles
No I ever ran it before and I'm aware of some sidesQuote:
Originally Posted by MuscleInk
Above question not answered....Quote:
Originally Posted by MuscleInk
No, it's not catabolic. Regardless of anything else you're using with it will not make it catabolic or anabolic. It does, however, have a slight anabolic nature but it is very slight and almost of no consequence in human beings.Quote:
Originally Posted by EarlyMuscles
Do you mean that it protects from muscle tissue being catabolized?Quote:
Originally Posted by ghettoboyd
Anabolic is different from being anti-catabolic, perhaps you mistook the terms.
Also, do you have a reference to this information?
yes bro i thought so my means of being anabolic, but even that is subject to debate as you know the studies where done with animals and at high doses....im not going to post a link...Quote:
Originally Posted by Sworder
Why would you not post a link?Quote:
Originally Posted by ghettoboyd
Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation
http://ajpendo.physiology.org/content/263/1/E50.short
Abstract
The potent anabolic effects of the beta 2-adrenoceptor agonist clenbuterol on skeletal muscle have been reported to be independent of actions on beta-adrenoceptors. In the present study clenbuterol, presented to rats in the diet (4 mg/kg), caused significant increases in gastrocnemius muscle mass, protein, and RNA content and a decrease in epididymal fat pad mass. These effects were not mimicked by oral administration of the beta 2-adrenoceptor agonist salbutamol even at high dose (52 mg/kg diet), and the effects of clenbuterol were not inhibited by addition of DL-propranolol (200 mg/kg diet). However, the selective beta 2-antagonist ICI-118,551 (200 mg/kg diet) reversed the anabolic effects of clenbuterol, and a high dose of DL-propranolol (1,000 mg/kg diet) also inhibited these actions of clenbuterol. Furthermore, continuous infusion of salbutamol (1.15 mg.kg body wt-1.day-1) via miniosmotic pumps did cause significant increases in muscle mass, protein, and RNA content. These results indicate that the anabolic effects of clenbuterol are dependent on interaction with the beta 2-adrenoceptor. However, a long duration of action appears to be required to induce the anabolic effects of beta 2-agonists.
MG not MCG...?
In my opinion it isn't really up for debate. In fact, based on these doses I would think that it would be rather, what's the word... Difficult to make a convincing argument for clenbuterol being anabolic let alone anti-catabolic..