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No More Letro for Gyno!
I see it all over. I have gyno..how much letro should i take? Jumping on letro to "crush"estrogen to the point that gyno can not survive. The problem is estrogen plays an important role in so many things the idea of simply "crushing"it is far from a prudent one.
This is where serms come in. Serms bind to the estrogen receptor in breast tissue, making it impossible for estrogen to bind and illicit its effects on those receptors. If we are getting gyno, even if using an ai, our estrogen levels are too high. They need to be managed, however with gyno at the door a serm will stop it in its tracks.
I think gyno treatment should be 2 fold , treatment and then management. The treatment and management should occur at the same time using a serm and an AI. The SERM will IMMEDIATELY begin to prevent and treat gyno. The ai will manage estrogen levels lowering them to a proper level where serm therapy may be stopped.
There is a lot of talk about tamoxifen and its effects on pogesterone or how it lowers blood levels of arimidex and letrozole . All that aside (i personally think its over hyped), one can use the serm Raloxifene which puts these fears to rest.
Gyno symptom? Lump etc. Start 60mg ralox/day and up ai dose as current dose was not adequately managing estrogen. When lump goes away cease serm use and continue on with elevated ai doages till end of cycle up to pct.
Thoughts?
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05-23-2013, 10:44 AM #2
I agree with the 2 shot method. Administering Nolva and letro worked great for me. I don't know if Letro is quite the devil some it's made out to be. It takes some practice to get used to dosing but it is a very effective AI
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05-23-2013, 10:44 AM #3
never tried ralox, Nolva works fine for me
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05-23-2013, 10:52 AM #7
I think the point of "crashing estrogen" during gyno reversal is to attack it hard and fast before it becomes permanent. I would rather deal with short term effects of low estrogen than a lifetime of gyno. I'm not arguing your op just pointing out my reason for choosing letro originally.
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05-23-2013, 10:54 AM #8
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05-23-2013, 10:59 AM #9Banned
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Never used ralox either. Heard goof things
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05-23-2013, 11:09 AM #10
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05-23-2013, 11:19 AM #11
I always use nolvadex as well as my A.i during cycle. I'm very sensitive to high estro and usually have a flare up mid cycle. Never used ralox but open to new ideas
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05-23-2013, 11:20 AM #12
When I searched for information about raloxifene on the forum I found this. http://forums.steroid.com/questions-...treatment.html
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05-23-2013, 11:30 AM #13
I agree. I am not a fan of Letro even for an AI. Juiced Porkchop is a very advanced, responsible and level headed user with a great understanding of Letro and it's effects. This is why I never say anything about his use, but I don't recommend it for the average gym goer.
Ralox is absolutely superior of the 3 mentioned, and the protocol starting at 60mg is perfect. This will take time of course, so be patient and don't lose hope... it will work!~ PLEASE DO NOT ASK FOR SOURCE CHECKS ~
"It's human nature in a 'more is better' society full of a younger generation that expects instant gratification, then complain when they don't get it. The problem will get far worse before it gets better". ~ kelkel
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05-23-2013, 11:36 AM #14Member
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05-23-2013, 11:37 AM #15Member
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05-23-2013, 12:04 PM #17Member
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05-23-2013, 12:25 PM #19Originally Posted by seriouslifter
I seem to have worked my own dosage of A.i during cycle where I don't crash and sides are slight but still enough to warrant the use of a seem.
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05-23-2013, 01:04 PM #20
Agree with Jimmy 100%. Letro should be for the advanced user only IMHO. It's senseless to crush your E when safer options exist as noted above. Pubmed will bear out what Jimmy said regarding the effectiveness of Raloxifene having an edge over nolva. Some people just seem hyper-sensitive to gyno and slight deviations or jumps in their E levels can cause issues from sensitivity only to deposits. For these individuals running a serm along side their AI is just plain prudent. It's a safety net, so to speak, regardless if there is a loss in efficacy of the AI or not. Timely BW is prudent as always in these situations.
I've mentioned this here recently that I advised several friends of mine with developing gyno issues about the serm / andractim combo. Both had great success. One is a current pro who was obviously aware of serms but not of Andractim. Great stuff.
My .02 anyway.
Well said Jimmy!
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05-23-2013, 01:37 PM #21
Great and timely thread as we have had quite a few gyno threads of recent. I have managed estrogen while on cycle and have not had a gyno problem although very prone to estrogen conversion. I like idea of attacking the problem from different directions without sending estrogen to the grave. Thanks Jimmy for post this and starting the conversation.
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05-23-2013, 05:46 PM #22
quick side hijack, say I AM running 20mg Nolva for estrogen while on cycle, when going into a Nolva Clomid pct, how should I dose that Nolva to shock the system once again? hit 60mg for the first week?
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I personally have been using letro for my AI use, yes it took some tweeking and trial and eror, but It works great, and yes I do take 20 mg of nova when blasting a 19 nor. I have never had any type of gyno related anything......
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05-24-2013, 12:08 AM #24
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05-28-2013, 07:36 AM #25
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05-28-2013, 04:15 PM #26Member
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05-29-2013, 01:56 PM #27
Great write-up Jimmy, thanks.
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05-29-2013, 10:03 PM #28
Top.
~ PLEASE DO NOT ASK FOR SOURCE CHECKS ~
"It's human nature in a 'more is better' society full of a younger generation that expects instant gratification, then complain when they don't get it. The problem will get far worse before it gets better". ~ kelkel
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05-29-2013, 10:20 PM #29
I'm currently battling a little gyno flare up mid-cycle. I'm not sure really how this happened. I've been running .5 mg of adex, .3 mg of prami, and 20 mg of tamox (for lipids) ED. I am pretty certain it's gyno as it is a hard lump behind my nipple and is sensitive to the touch. Definitely not adipose tissue. I started taking 60mg of ralox about a week ago. My question is - How long until you start to notice the effects?
I just put in an order for some letro as I'm not going to let the progress any further. I've had great luck with nolva and letro in the past but was put on to raloxifene by all of the good reviews here. My main concern is that I have been taking nolva, adex and prami and still had this flare up. Any thoughts? Not a sufficient enough dosage of each? I felt like I was running them all on the high end.
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05-29-2013, 10:38 PM #30Originally Posted by JWP806
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05-29-2013, 11:06 PM #31Originally Posted by EKFitness
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05-30-2013, 08:06 AM #32Originally Posted by JWP806
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05-30-2013, 08:12 AM #33
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05-30-2013, 08:50 AM #34
Yeah, it could be... I don't think I'm on too much gear though... 500mg test, 450mg deca . At the dosages that I was taking of my a-dex, prami, and nolva, there is no way in hell I should have developed a lump. Definitely a relentless titty situation. wtf?
I reposted this question to gain some more traffic so I am going to stop commenting on this one.
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05-31-2013, 08:30 AM #35
Bump
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05-31-2013, 10:26 AM #36
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06-25-2013, 08:19 AM #37
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Shameless Bump....
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06-25-2013, 08:46 AM #38
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07-09-2013, 08:55 AM #39
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07-09-2013, 11:27 AM #40Junior Member
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great thread, thanks!
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