Synthyroid (T4)

[ChiveOn]

So, I don't normally take things from friends but a buddy of mine had some synthyroid 125mcg that he didn't want/need anymore.
I've taken T3 on cycle before at 100mcg daily so I've used a similar compound but I don't plan on cycling for at least another year.
Is it worth hanging onto it or can I take it off cycle?
At 125mcg, it should convert into about 31.25~mcg of T3 correct?
Can I take it at 250mcg of synthyroid off cycle? It'll only be about two weeks worth...
Just looking for you .02 I may not even take it from the guy, but it's free so hard to just say no unless I have a good reason

[OnTheSauce]

Are u taking hgh?

[ChiveOn]

Nope
Ill never touch slin and probably not HGH either.

[OnTheSauce]

Then I wouldn't use it

[ChiveOn]

Ok. I'm curious as to the reasoning behind that

[OnTheSauce]

Why mess with your thyroid?

[ChiveOn]

Well I took T3 for 6wks with my test tren cutting cycle.
Are you against T3 as well as T4?

[OnTheSauce]

T3 is catabolic and shouldn't be used off cycle. And 100mcgs is too high at anytime IMO. The only reason for messing with thyroid off cycle would be if running a decent hgh dose. And you would use t4

[marcus300]

It doesn't mess up your thyroid but I would take it with anabolics just incase your diet isn't in tune

[OnTheSauce]

It doesn't mess up your thyroid but I would take it with anabolics just incase your diet isn't in tune

Does t4 not alter it like t3 does? I've only used t4 in conjunction with hgh and never used t3

[marcus300]

Does t4 not alter it like t3 does? I've only used t4 in conjunction with hgh and never used t3

All T-hormones effect your thyroid ifn you take enough of them but they don't mess it up, it rebounds perfectly without any issues. There are studies available what show years on t3/T4 and the thyroid rebounds easily.

[ChiveOn]

I had always read that after usage everything bounced back a lot faster than you would think.
Anyways, I'm not on cycle anyway so I don't think it's worth my time. I had just never come across T4 before so I was curious to the comparison.
Thanks for your input guys

[555mjolnir]

I believe it converts @ 80% so 125mcgs converts to 100mcg of t3 so t4 @ 250 = t3 @ 200 and that is probably to much. imo

[The Deadlifting Dog]

I believe the conversion rate is actually 25%.

So 100mcg of T4 converts to 25mcg of T3
125mcg T4 converts to 31.25mcg T3
250mcg T4 converts to 62.5 mcg T3

I am sure on of the veterans will clear this up.

[ChiveOn]

I have never heard it being this high. I thought it was around 25%

Anyone else have a differing opinion. Who's right here?

[555mjolnir]

here is some info I found take or leave it...but here it is. link posted to site is below info.

Thyroid Metabolism

After the hypothalamus stimulates the pituitary, and after the pituitary releases TSH, and after thyroid peroxidase makes T3/T4 in the thyroid, T3 and T4 is released into the blood and catches a ride on a protein called Thyroid Binding Globulin which acts as a taxi to transfer the hormones.

Roughly 93% of the thyroid hormones is in the form of T4 which is an inactive form and must be converted to T3 before the cells of the body can use it. 7% is made into T3 and can be imediately transfered to cells by thyroid binding glubulin proteins.

In the liver, around 60% of the inactive T4 is converted to T3. Another 20% gets converted to reverse T3 which is inactive and exctreted from the body. The last 20% is converted to T3S and T3AC which are inactive forms of T3.

T3S and T3AC are then converted into the active form of T3 by bacteria located in the gastrointestinal tract. It can then be used by the cells of the body to fuel metabolism.

Thyroid Metabolism: Click for Larger Image


Milwaukee Thyroid Relief & Wellness

this one is even better but a longer read

http://drhedberg.com/2011/02/08/the-...roid-hormones/

both talk of 80+% conversion by the time the process is complete- 7% immediately converted, 60% converted in Liver, and 20% that is converted to t3s and t3ac converted to useable t3 in gastro intestinal track.

With the power of thyroid drugs please be careful and research don't just ask others who just grab from out of thin air.