1mg liquidex (anastrazole) a day...?

[20YO]

hi guys, im currently on week 6 of a 500mg/week test e cycle. Im currently taking 15mg clomid every day and 0.5mg liquidex every day. However, I notice my nipples have been quite puffy lately, ive got a bit of water retention going on... and my libido is way down from where it was at the beginning of this course. I am tempted to up my liquidex to 1mg a day...
I am concerned though, because this seems like a rather high dose. Any ideas?
Has anyone run liquidex at this dose before...?

[austinite]

Less guessing and more blood work. That's what I would do.

[MuscleInk]

hi guys, im currently on week 6 of a 500mg/week test e cycle. Im currently taking 15mg clomid every day and 0.5mg liquidex every day. However, I notice my nipples have been quite puffy lately, ive got a bit of water retention going on... and my libido is way down from where it was at the beginning of this course. I am tempted to up my liquidex to 1mg a day...
I am concerned though, because this seems like a rather high dose. Any ideas?
Has anyone run liquidex at this dose before...?

At .5mg per day you may already have dropped your E2 too far. Low and high E2 produce similar effects.

Why are you running clomiphene during your cycle anyway?????

[20YO]

running the clomiphene to help with ball shrinkage... and it sorta seems to have helped. also running it for the nips issues... should i not be running it?
I had a blood test done 2 weeks into my course... and that day id just happened to have 1mg adex. E2 came back at 80 (range was <150) and i felt pretty good then.
I also have elevated progesterone (this was high befroe going on cycle) so keeping e2 down seems prudent. as you say, though, i dont want to crash it

[MuscleInk]

running the clomiphene to help with ball shrinkage... and it sorta seems to have helped. also running it for the nips issues... should i not be running it?
I had a blood test done 2 weeks into my course... and that day id just happened to have 1mg adex. E2 came back at 80 (range was <150) and i felt pretty good then.
I also have elevated progesterone (this was high befroe going on cycle) so keeping e2 down seems prudent. as you say, though, i dont want to crash it

Clomiphene has anti-estrogenic properties so taken together (AI+clomid) you are blocking more E2 than necessary. Unless you plan on more BW as Austinite suggests, I'd drop the clomid and go with adex at .25mg EOD and see what improvements are achieved.

[MuscleInk]

Are you running HCG? THIS (not clomid) will help with testicular atrophy. Clomid primarily helps with spermatogenesis.

[20YO]

so clomid will drop e2?? this is news to me
can low e2 really manifest as nipple puffiness, bloating etc?
I will get another blood test tomorrow whilst on 0.5mg/day and see what it comes back as... i would love to only to 0.25 eod but i have a feeling i am highly estrogen prone....

[AD]

whats your age and bf%?

may have to check your E2 again, the last one being 4wks ago.

clomid is rather mild. taking it while on 500mg/wk of test will probably give you not much effect. for gyno management while on cycle, you may have to use tamox or ralox. for ball shrinkage, try hcg.

edit: hey MI, hows it going?

[20YO]

nah im not on hcg.... i want to get my hands on it but its hard to find in AU. The thinking behind clomid was that it blocks the negative feedback process associated with exogenous test use, thereby maintaining some sorta endogenous production, thereby maintaining some nad size.
all i know is since upping the ai and throwing in some clomid, my nads have improved.

[20YO]

thanks for your post AD, defs looks like more bloods are in order. Im 20 years old. BF is at approx 15%

[MuscleInk]

whats your age and bf%?

may have to check your E2 again, the last one being 4wks ago.

clomid is rather mild. taking it while on 500mg/wk of test will probably give you not much effect. for gyno management while on cycle, you may have to use tamox or ralox. for ball shrinkage, try hcg.

edit: hey MI, hows it going?

Hey AD! Busy as heck these days. How you keeping?

OP.....gyno can also be genetic. Some men are more prone to it than others. As AD points out, raloxifene is the gold standard for gyno, IF you in fact have gyno. Water retention is not gyno.

[AD]

thanks for your post AD, defs looks like more bloods are in order. Im 20 years old. BF is at approx 15%

at that age and bf%, theoretically you level of aromatisation should not be very high. which means most likely your AI dose is too high. but if you're still getting possible gyno at that dose, the other possibility is that your AI may be bunk.

and of cos, you probably should not be doing gear at that age

[MuscleInk]

nah im not on hcg.... i want to get my hands on it but its hard to find in AU. The thinking behind clomid was that it blocks the negative feedback process associated with exogenous test use, thereby maintaining some sorta endogenous production, thereby maintaining some nad size.
all i know is since upping the ai and throwing in some clomid, my nads have improved.

At 500mg/wk, you will cause a flare response that will down regulate your endogenous test via the HTPA - a process similar to androgen blockade with products like flutamide and bicalutamide that are GnRH agonists.
The AI prevents conversion of excess test to estrogen.

[20YO]

yeah there are pea sized lumps mate as well as the puffiness. had some issues way back when i was 14/15 but it sorta self resided.
I cant get my hands on raloxifene but probs can get my hands on tamoxifen. Still id rather have e2 levels under control rather than (potentially) high e2 and switched off receptors in my chest.
nip issues aside, at 500mgs test a week i should have awesome libido, but this is not the case, which is equally if not more troubling

[MuscleInk]

yeah there are pea sized lumps mate as well as the puffiness. had some issues way back when i was 14/15 but it sorta self resided.
I cant get my hands on raloxifene but probs can get my hands on tamoxifen. Still id rather have e2 levels under control rather than (potentially) high e2 and switched off receptors in my chest.
nip issues aside, at 500mgs test a week i should have awesome libido, but this is not the case, which is equally if not more troubling

Raloxifene is gold standard. Femara is sometimes used but less effective and very harsh.

Blood work recommended.

[20YO]

yeah i appreciate that AD. I was initially on trt because my t level was 12 (range of 12-30) with no prior AAS use. Doc took me off trt after a month because he changed his mind....
Then shut down i decided to start self administering... got a bit carried away and here i am now haha

[AD]

wow, trt is a rather complicated subject, and not easy to self-administer correctly and safely.

you can consider giving LowTdotcom a call and see what they can offer. and definitely visit the TRT forum here.

good luck

[20YO]

and thanks muscle ink.. will drop the clomid for now and get on hunt for a better serm.... bloods results to follow later in wk...

[20YO]

yeah im well aware ad, believe you me. i defs felt better on the t tho. Pretty clear my borderline deficiency was causing probs.... yet most docs over here are too dumb, too scared (or both) to prescribe.

im from australia, so i dont think lowtdotcom can be of much help unfortunately.