Newbie, multiple sclerosis sufferer with a serious question

[catburgers]

I'm 29, been lifting for about 6 years now but have experienced an extreme setback in my lifting: multiple sclerosis.

I was diagnosed at 19. I had a big attack/episode in April/May of 2012 and again in May/June of 2013. I lost control of both hands and a good portion of my torso and shoulders. I also get very bad lhermitte's sign (you bend your neck and get electric shocks jolting throughout your body). After about 6 weeks of the onset of an attack my body begins to repair at a snails pace and I can start to feel my fingers or my skin again. Motor function returns just as slowly...if at all.

My strength has been declining and nonexistent, my fatigue has been through the roof and my coordination has been steadily declining. I need my life back.

Most of my symptoms are remarkably similar to low testosterone: fatigue, mental fog, libido issues, strength losses, coordination problems, weight gain, no cardiovascular endurance, extreme problems losing weight, inability to well...do much of anything.

So back in June I did something crazy: I started taking clomiphene just for the hell of it. 50mg a day. After day 10-13 I noticed dramatically less fatigue, strength increases (back to my pre-devastating attack levels), increased endurance, mental fog cleared up, vision in my eye damaged by optic neuritis actually improved and a whole host of other improvements. I felt like *me* again. I could tell that my natural testosterone level was bumped (got zits on my forehead). I did *not* get lab work.

The downside? After about 20 days on clomiphene I noticed that I was not getting beneficial effects anymore and the depression/mania/mood swings were intolerable. After another 10 days I stopped clomiphene. My temporary MS symptom relief was over and I was left with extreme fatigue, difficulty walking again, difficulty swallowing, etc.

This is the crazy crazy question. Does it make any sense that testosterone could be beneficial to the nervous system to perhaps allow me to live a "normal" life? I'm seeing an endocrinologist soon...and I want my life back.

Post your thoughts please!

[Necromanncer]

Good luck with your journey.

I can't offer advice, but encouragement.
I have a friend going through the same thing with her husband.

I want to offer her advice and I'm going to follow this close. Good luck, good attitude bro. Answers are out there!

[catburgers]

So I had my testosterone levels checked back in 2009. My doctor never sent me the results -- only gave me a "thumbs up". I just got the nurse to print the results out:
Collection time: 07:25 6/26/2009
TSH:
2.31 range 0.45-4.50 uiu/ml
T4 Free:
0.9 range 0.6-1.6 ng/dl
Testosterone:
321 range 241-827 ng/dl

So at the age of 25 at 7:25 in the morning I'm on the low end of the reference range.

I'm seeing an endocrinologist on Sept 9.

[AnabolicBoy1981]

Your testosterone level sucks. Id get another test and if its similar go for trt eval.

Second, my first inclination to your improvement was not som much increased testosterone, but maybe lack of estrogen, as women are afflicted with this disease more often than men are. Estrogen increass the immune system and since your immune system is attacking you in MS, hence the lowered or "blocked" estrogen in your case worked. Clomid only blocks selectivly tho, so now im thinking it could be the increase in testosterone that did it for you. Im curious what arimidex would do. i have also read a study where Bromocriptine, another drug we muscle heads use helped MS patients. Its an dopamine agonist and antiprolactin. Conversly in women prolactin helps MS.

[catburgers]

Sorry, posted twice. Ignore this post.

[catburgers]

The clomiphene worked on my pituitary and hypothalamus and occupied receptors. If anything it increased the levels of GNRH which led to increased LH. The increased LH levels then resulted in an increase in test levels. The increased test aromatized to estrogen. There was no immune system dis-regulation -- I did not experience a new exacerbation.

I experienced a remission of old attack symptoms. Something about the boosted testosterone level increased nerve conductivity which would explain why my vision got better from a damaged optic nerve.

If anything the clomiphene probably increased the level of estrogen in my system.

[AnabolicBoy1981]

i have healed a damage nerve with high doses of test. I think most of it is accomplished through DHT but estrogen has a place too from the studies ive seen. Wondering if DHT derived drugs are ideal for nerve repair. I think anavar especially would be good. Primobolan i was disappointed in for nerve healing. Curious what masteron would do. For you i might suggest keeping short acting versions of test. prop or ace or TNE, and mast prop, tren ace maybe even, so you can admister short cycles for healing. Even T-bol and d-bol might be good. D-bol stimulates GH too which might be a benefit.