Nolva on cycle with AI?

[Machdiesel]

Ok so I have never cycled before but recently was put on trt. At 120 mg of test a week my estradiol was only slightly high out of range at 51 and I started getting itchy nips and slight gyno. Went to doc and got an AI to get estrogen under controll and used some nolva from board sponsor. Worked great and im fine now. Clearly I am very gyno sensative so my question is for my first cycle of 500mg test and 30mg dbol should I run nolva along with my 25mg a day of exemestane? My Main question is can gyno form even if i keep estrogen under control? Would this be a good Addition to soemome Who is prone to gyno. I know it Was Reccomended in the past but that was before people really used AIs.

[Schwarzenegger]

Ok so I have never cycled before but recently was put on trt. At 120 mg of test a week my estradiol was only slightly high out of range at 51 and I started getting itchy nips and slight gyno. Went to doc and got an AI to get estrogen under controll and used some nolva from board sponsor. Worked great and im fine now. Clearly I am very gyno sensative so my question is for my first cycle of 500mg test and 30mg dbol should I run nolva along with my 25mg a day of exemestane? My Main question is can gyno form even if i keep estrogen under control? Would this be a good Addition to soemome Who is prone to gyno. I know it Was Reccomended in the past but that was before people really used AIs.

I use nolva on every cycle with an AI. Better safe than sorry. Some people say u don't need it. I'm prone to gyno and even if u have estrogen in range, its still floating around. i got surgery to get rid of puberty gyno so i dont want that shizzz coming back.

20mg nolva/day should be good along with AI

[Docd187123]

I use nolva on every cycle with an AI. Better safe than sorry. Some people say u don't need it. I'm prone to gyno and even if u have estrogen in range, its still floating around. i got surgery to get rid of puberty gyno so i dont want that shizzz coming back.

20mg nolva/day should be good along with AI

It is still floating around even wih an AI but estrogen is also needed. I wouldn't necessarily consider it safe to use it if you don't need it.

[kelkel]

I think you should consider getting dialed in on your TRT first and ride out the gains you can make from that before you consider a cycle. You can really make positive gains just by restoring your natural T levels. Also, before considering an AI you should evaluate your numbers and see if a slight dose reduction (gasp!) would help alleviate the need for the AI. Trust me, you won't feel the difference in a few points of total testosterone. Use your free T as your guide.

Doesn't take much sometimes to make a difference and if you can dial in your TRT without an AI then it's a win-win.

[Machdiesel]

^ cycle is 6 months away, just getting prepared . Was on 100mg a week and test was 550 with free test on the low side and E2 36. Upped it to 120 mg but got sensative nips and slight gyno, BW came back total test 678, E2 50. Doc messed up and didn't get free T . So even at 120 I need an AI. Starting 140mg a week, 12.5 mg exemestane MWF, blood work in 4 weeks. Ideally total test 800-840, free T I forget range but it was on the very low side at 100mg, would like to be at the mid/upper range, and E2 20-25.

[manky chops]

Ok so I have never cycled before but recently was put on trt. At 120 mg of test a week my estradiol was only slightly high out of range at 51 and I started getting itchy nips and slight gyno. Went to doc and got an AI to get estrogen under controll and used some nolva from board sponsor. Worked great and im fine now. Clearly I am very gyno sensative so my question is for my first cycle of 500mg test and 30mg dbol should I run nolva along with my 25mg a day of exemestane? My Main question is can gyno form even if i keep estrogen under control? Would this be a good Addition to soemome Who is prone to gyno. I know it Was Reccomended in the past but that was before people really used AIs.

if you dont mind me asking whats your bodyfat % and weight? sorry just a curious person being curious

[Bio-Active]

^ cycle is 6 months away, just getting prepared . Was on 100mg a week and test was 550 with free test on the low side and E2 36. Upped it to 120 mg but got sensative nips and slight gyno, BW came back total test 678, E2 50. Doc messed up and didn't get free T . So even at 120 I need an AI. Starting 140mg a week, 12.5 mg exemestane MWF, blood work in 4 weeks. Ideally total test 800-840, free T I forget range but it was on the very low side at 100mg, would like to be at the mid/upper range, and E2 20-25.

Your aromasin should be run Ed

[Machdiesel]

208lbs, 15% and dropping. Goal is 10% then slowly bulk for a few months. Then get back down to 10-12% and hit the cycle. So you recomend a 1/4 pill ED.? That's 6.25 ed

[Docd187123]

208lbs, 15% and dropping. Goal is 10% then slowly bulk for a few months. Then get back down to 10-12% and hit the cycle. So you recomend a 1/4 pill ED.? That's 6.25 ed

Probably means 12.5mg ED.

[Machdiesel]

^ seems high for a trt 70mg of test C twice a week . For the proposed cycle I plan on 25mg a day

[Docd187123]

^ seems high for a trt 70mg of test C twice a week . For the proposed cycle I plan on 25mg a day

Exemestane is not as potent as adex and there's evidence to suggest a shorter half life in men than women. But it very well could be too much AI for you, blood work is the only way to tell though.

[ANIMAL]

I've been on my current cycle for 12 weeks, just Test 500mg/week. I started my stane dose at 12.5mg ED and I'm currently up to 20mg ED. I ran that with Raloxifene 60mg ED to get rid of my gyno lump. The Ralox has done nothing since day 1 and the gyno has gotten a bit worse. I stopped taking the Ralox 2 days ago and started with nolva for 40mg to get rid of the lumps. In 2 days they have already started to go down with sensitivity next to nothing. Once I get the lumps down I'll bring the nolva to 20mg ED and finish the cycle with it. I think from now on I will be using 20mg nolva in every cycle being that I'm so sensitive to gyno. Waiting on blood work at the moment to come back.

[Machdiesel]

Possible your RALOX a bunk? I've been taking 2ml of arr nolva for 10 days and seems to be working for my slight gyno. I'm due for another bottle in a week and saw they had RALOX back in stock so got 2 bottles, once those are done hoping I'll be G2G . Gonna do 120mg first few days then 60 untill the bottles run out

[Machdiesel]

I've read stane is a suicide inhibitor you can take it EOD. I guess theory being your body won't over produce in 24 hours. Obviously I'd like to keep the dose as low as possible. 12.5 mg EOD was my first thought, MWF is just a way easier schedule. Maybe MWF and Saturday

[Docd187123]

I've read stane is a suicide inhibitor you can take it EOD. I guess theory being your body won't over produce in 24 hours. Obviously I'd like to keep the dose as low as possible. 12.5 mg EOD was my first thought, MWF is just a way easier schedule. Maybe MWF and Saturday

It is a suicidal inhibitor but the body is constantly making new enzymes to aromatize. Use blood work to help you determine proper dosing regardless of it's suicidal-like properties

[Machdiesel]

Ya need to figure out a way to get bloods. Had 3 done from endo the past few months he said he'd only re test In 6 months and already used up my yearly physical from my GP to track E2

[kelkel]

If you're in the states there are private labs available.

[Machdiesel]

I live in nj. Tried to sign up for a lab in PA but billing address has to match ID, and you have to have an ID from that state

[Docd187123]

I live in nj. Tried to sign up for a lab in PA but billing address has to match ID, and you have to have an ID from that state

You do NOT need to live in that state. I had a guy from Montreal go to a labcorp location in Vermont and he was able to do it.

[Machdiesel]

The online form for privatelabsmd says billing adders an mailing address must match, so didn't even bother . Il fill it out , use a fake PA address, and try my debit card and see if it works. When I go I'll just say I recently move to PA. How's that idea look guys ?

[Machdiesel]

Or can I use all my real info?

[Machdiesel]

This

[Docd187123]

The online form for privatelabsmd says billing adders an mailing address must match, so didn't even bother . Il fill it out , use a fake PA address, and try my debit card and see if it works. When I go I'll just say I recently move to PA. How's that idea look guys ?

Just use your address and select a labcorp location in PA that's close to you. You cannot get private bloods in NJ but you also don't need to be a resident of the state to wish to get the blood work in. Use your real info and pay for it online. Select a labcorp location near you outside of NJ and NY. When you get there you may need id but if they ask for insurance info or a CC just tell them it's been prepaid.

[Docd187123]

This

They can't give it to residents of those states who wish to get it done in those states. You can be a non-resident and go to another state for it though.

[Machdiesel]

The fact it says it can not provide services for residents of nj makes me Leary. Worst case i guess I waste an afternoon. So the female hormone panel doesn't have free T so I'm gonna use this one " Hormone Panel with F&T Testosterone LC/MS-MS Add to Wishlist $99.99
More Info Add To Cart

Look good?

[Docd187123]

The fact it says it can not provide services for residents of nj makes me Leary. Worst case i guess I waste an afternoon. So the female hormone panel doesn't have free T so I'm gonna use this one " Hormone Panel with F&T Testosterone LC/MS-MS Add to Wishlist $99.99
More Info Add To Cart

Look good?

Like I said I've had a member from Canada come to the states and do it as well as NJ, NY, and mA residents who went to other states.

[Machdiesel]

^ ya missed that thank you, huge relief

[probuild42]

I use a local lab, all they do is bloodwork. Go in pay, they draw blood on site. They send your results in about 3-5 days. They are easy to work with. Google blood work in the area you live and there may be a something close to you.

[Machdiesel]

Privatelabsmd can't be done with a person who's address/mailing address/ billing address is NJ

[Machdiesel]

This may take a bit more leg work. Im assuming the website can't
Take payment or send info to nj residents. Tne actual lab corp won't care where my id is from because they are only doing the blood draw. Might have to find the closest la corp in PA , drive there and find tne nearest post office and get a Po box. This way I can use tnat for everything . Anyone have an easier way?

[Docd187123]

This may take a bit more leg work. Im assuming the website can't
Take payment or send info to nj residents. Tne actual lab corp won't care where my id is from because they are only doing the blood draw. Might have to find the closest la corp in PA , drive there and find tne nearest post office and get a Po box. This way I can use tnat for everything . Anyone have an easier way?

You don't need to go through all that. Another guy I know drove from NJ to PA to do it and had no issues.

[Machdiesel]

How did he process it on their site? It ask for your address and residence. Under the pulldown menu NJ isn't even listed so I can't put it my real address. It claims billing address has to match patient info listed so can't just make a bogus pa address? Look at the pic I posted above, at the top of the page it says billing info must match patient info, how would I fill it out

[MR10X]

Estrogen rebound is a myth,your body tries to keep an Estrogen/testosterone balance.The more test you have in your system the more E your body will make.Your test levels will depend on what day you have blood drawn,the closer to the day you inject the higher the levels will be.Long esters done weekly have higher peaks and lower lows compared to twice weekly.I was doing 120 mg test E weekly and blood tested on third day after inject was 1580 TT (348-1197)and 26.7 FT (6.6-48.1),E2 was 17.2 (25-50).I was using no AI or Serms or other steroids,this was TRT only.

[Juced_porkchop]

Ok so I have never cycled before but recently was put on trt. At 120 mg of test a week my estradiol was only slightly high out of range at 51 and I started getting itchy nips and slight gyno. Went to doc and got an AI to get estrogen under controll and used some nolva from board sponsor. Worked great and im fine now. Clearly I am very gyno sensative so my question is for my first cycle of 500mg test and 30mg dbol should I run nolva along with my 25mg a day of exemestane? My Main question is can gyno form even if i keep estrogen under control? Would this be a good Addition to soemome Who is prone to gyno. I know it Was Reccomended in the past but that was before people really used AIs.

stick with AI on cycle. if you have a flair up then up AI dose and run low dose nolva for 1-2 weeks while AI take affect. thats what i rec

[MR10X]

Also, there have been some additional researches related to Aromasin in men in pharmacokinetics. The results of the research are the following:

24 hours after one 25mg dose, estrogen levels are reduced by 70-80%;

72 hours later estrogen levels are still 40% below the baseline;

120 hours after initial dose, estrogen levels return to baseline.

Additionally, the University of Florida conducted a study in healthy young men:

Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males.

Nemours Children’s Clinic and Research Programs (N.M., J.L., A.R.), Jacksonville, Florida 32207; and University of Florida Health Sciences Center (D.P.) and Amersham Pharmacia Biotech (E.d.S., A.K., B.L.), Peapack, New Jersey 07977

To characterize its suppression of estrogen and its pharmacokinetic (PK) properties in males, healthy eugonadal subjects (14–26 yr of age) were recruited. In a cross-over study, 12 were randomly assigned to 25 and 50 mg Aromasin daily, orally, for 10 days with a 14 day washout period. Blood was withdrawn before and 24 hours after the last dose of each treatment period. A PK study was performed using a 25mg dose. Aromasin suppressed plasma estradiol comparably with either dose [25 mg, 38%; 50 mg, 32%], with a reciprocal increase in testosterone concentrations (60% and 56%; for both).

The following observations were made:

Plasma lipids and IGF-I concentrations were unaffected by treatment.
The PK properties of the 25-mg dose showed the highest concentrations 1 h after administration, indicating rapid absorption.
Maximal estradiol suppression of 62 ± 14% was observed at 12 h.
The drug was well tolerated.
The terminal half-life was 8.9 hours in the male subjects.
In conclusion, Aromasin (Exemestane) is a potent aromatase inhibitor in men and an alternative to the choice of available inhibitors. Long-term efficacy and safety will need further study.

References and Supporting Data:

A predictive model for exemestane pharmacokinetics/pharmacodynamics incorporating the effect of food and formulation.Br J Clinical Pharmacology. 2005 Mar, 59(3):355-64.

Eur. J. Cancer. 2000, May;36(8):976-82

The Journal of Clinical Endocrinology & Metabolism Vol. 88, No. 12 5951-5956Copyright © 2003 by The Endocrine Society

Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S

Anticancer Res. 2003 Jul-Aug;23(4):3485

J Clin Endocrinol Metab. 2003 Dec;88(12):5951-6.

[Machdiesel]

Dosing 6.25 ED and feeling great, noticable Sex drive increase and no itchy nips. Might have to wait a few months to get BW done if I can't figure out a way to use privatelabsmd