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Thread: Shutdown of the HPTA, best methods of prevention??

  1. #1
    workoutho is offline New Member
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    Shutdown of the HPTA, best methods of prevention??

    Ok, So this is a serious topic that everyone is curious about and the more and more i read about it the more i see there are conflicting views and unanswered questions.

    So as I am a beginner, researching my 1st cycle, you will see beginner questions. BUT questions that may are probably thinking as well if you are seriously concerned about your recovery!

    While cycling with test, the body realizes it already has enough test and stops producing its own, shutting off the release of LH. This in turn causes the testes to become desensitized and inactive because No LH-->No Test-->No testicular function.

    Now I know HCG is a good treatment on cycle as it mimics the LH and causes the testes to feel "mock LH" signals and produce natural testosterone . In this manner testicular atrophy and desensitization is prevented or at least greatly decreased. But what about the body's ability to produce LH while on cycle? is this ever staggered by using Test? Or does LH start producing rather rapidly following a cycle? I'm aware that Clomid/nolva are also used for this purpose during PCT but is there some compound that could stimulate LH production even during exo-test? Or would the use of a synthetic LH be even more confusing to the HPTA system. and requires even more time/effort for the body to recalibrate itself. I'm also wondering the same thing for GNRH. Would a synthetic GNRH be better than HCG or a synthetic LH?

    Hope that some of the seniors will pitch in to give the newbies advice. Some scientific studies would be much appreciated. Thanks for all your time in advance!

    Looking forward to making my brain stronger

    Best Evening to you all!

  2. #2
    austinite's Avatar
    austinite is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~
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    Best way to prevent shut-down is to:

    1. Start believing in God.
    2. Ask God to change the way your body works.
    3. Wait for God to reply.

    On a serious note, it's entirely rare to have a super hypersensitive HPTA where SERMS may still work in the presence on exo test. What we do now is the best method with respect to how much we've developed.
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    ~ PLEASE DO NOT ASK FOR SOURCE CHECKS ~

    "It's human nature in a 'more is better' society full of a younger generation that expects instant gratification, then complain when they don't get it. The problem will get far worse before it gets better". ~ kelkel

  3. #3
    workoutho is offline New Member
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    Sorry I just want to make sure I understand. You mean to say its rare to have a super hypersensitive HPTA and SERMS i.e. clomid, novla usually do the job of kicking the HPTA system back into gear?

    thanks

  4. #4
    Henrydot is offline New Member
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    HPTA will always shut down. you can only minimize it, or use hcg and ai so that during pct hpta will recover more smoothly

  5. #5
    Stealthypickle9 is offline New Member
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    so if you use hcg correctly on cycle and follow up with serms, will your natural test always return to baseline? not counting the people who already had a shotty hpta.

  6. #6
    Times Roman's Avatar
    Times Roman is offline Anabolic Member
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    to prevent shutdown, do not take steroids

  7. #7
    MuscleInk's Avatar
    MuscleInk is offline Knowledgeable Member
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    Quote Originally Posted by Stealthypickle9 View Post
    so if you use hcg correctly on cycle and follow up with serms, will your natural test always return to baseline? not counting the people who already had a shotty hpta.
    No. Plenty of members here under 25 who ran a proper cycle despite being told not to due to their age who did not recover and are now on TRT for life.

    Once you suppress your HTPA, all bets are off.
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  8. #8
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Quote Originally Posted by workoutho View Post
    Sorry I just want to make sure I understand. You mean to say its rare to have a super hypersensitive HPTA and SERMS i.e. clomid, novla usually do the job of kicking the HPTA system back into gear?

    thanks
    He means serms will do absolutely nothing for you regarding LH while running exogenous testosterone .
    -*- NO SOURCE CHECKS -*-

  9. #9
    lovbyts's Avatar
    lovbyts is offline Knowledgeable Member
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    Quote Originally Posted by Stealthypickle9 View Post
    so if you use hcg correctly on cycle and follow up with serms, will your natural test always return to baseline? not counting the people who already had a shotty hpta.
    Easy answer, No. If the answer was yes we would not have people asking on a daily basis for help. Nothing is guaranteed and some people just have bad luck.

  10. #10
    NACH3's Avatar
    NACH3 is offline VET
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    Quote Originally Posted by austinite View Post
    Best way to prevent shut-down is to:

    1. Start believing in God.
    2. Ask God to change the way your body works.
    3. Wait for God to reply.

    On a serious note, it's entirely rare to have a super hypersensitive HPTA where SERMS may still work in the presence on exo test. What we do now is the best method with respect to how much we've developed.
    Aust,

    If we had the ability to get real LH(like in a class one scientific lab) could that in fact take hCG 's place as it only mimics LH... And to actually have a real LH ONLY injectable(that would work in comparison to hCG(meaning following all protocols for hCG, but w/actual real LH)?? Just curious?

  11. #11
    Bonaparte's Avatar
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    In order to maintain gnrh production, you would need a drug capable of blocking androgen, estrogen, and progesterone receptors at the hypothalamus.

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