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Thread: Prolactin

  1. #1
    J703 is offline New Member
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    Jan 2015



    4th cycle with tren finished, E2 was in check, no lumps or soreness but lactating.
    What can I do?

    Been running Nolva for 3 weeks and it looks a tiny bit better.

    I used caber 1mg week and stane 25mg ED
    tren was at 525mg

    Also running HGH, peptides, T3 and T4
    Last edited by J703; 01-19-2015 at 05:55 PM.

  2. #2
    Ashop's Avatar
    Ashop is offline Anabolic Member
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    Jun 2005
    Get some lab work done first and then treat from there.
    You may want to try 1/2mg 2 x per week (MON/THUR)
    PT likes this.

  3. #3
    J703 is offline New Member
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    Jan 2015
    Quote Originally Posted by ALIN View Post
    Get some lab work done first and then treat from there.
    You may want to try 1/2mg 2 x per week (MON/THUR)
    Was using .50mg twice a week. 8 weeks while on Tren .
    I thought it was water retention at first because there were no lumps or soreness. My E2 was in my sweet spot, a tad high on blood panel, but that's where my body responds best. I'll get blood panel tomorrow then, obviously prolactin is high. Then should I try to knock the prolactin down with caber still?

  4. #4
    lovbyts's Avatar
    lovbyts is offline Knowledgeable Member
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    Apr 2008

    Prolactin in Men:
    Explanation and Purpose

    First thing... there is no such thing as "prolactin-induced" gynecomastia . I've heard this one too many times and later in this segment you will understand why. Now, prolactin is another sex hormone and is secreted by the pituitary gland in your brain. Although it's found in both males and females, it's main purpose is for milk production for females. The fact is, males have no use for prolactin that we know of today. Why, God, why?? Anyway, while low levels are not harmful, high levels certainly are. So let's take a look at the concerns with higher than normal prolactin levels in men...

    Effects of High Prolactin Levels in Men:

    - Adverse Testicular Interference
    - Lowers natural testosterone
    - Lower sperm count (to infertility levels)
    - long term elevation can cause erectile dysfunction (sometimes short term)
    - Low Libido
    - Breast tenderness
    - Male lactation
    - Low ejaculate volume

    19-Nortestosterone steroid such as nandrolone and Trenbolone can cause prolactin levels to become elevated MAINLY with the presence of excess estrogen. They are NOT a direct cause of high prolactin. While using prolactin inhibiting drugs will resolve issues, your first line of defense is controlling estrogen, as elevated estrogen can boost the effect of prolactin increase. It's not uncommon to prevent prolactin increase with the use of an AI. But the doses of 19-Nor steroids today, may prove that is somewhat ineffective. Leading to the necessity of having a secondary (and direct) compound to combat the effects.

    The way it works is entirely complicated and I couldn't even think of a way to put it in laymans terms. But in short, 19-Nor interaction with the estrogen receptors will boost prolactin secretion. This is why it's important to control estrogen first, and prolactin second. Also why I recommend that you have a secondary combat drug "on hand" and in some cases, used on cycle. You might wonder why I say "on hand", since I earlier said that low prolactin is not harmful. Well, these drugs have some fairly heavy side effects and if not used properly can really affect your progress on cycle. So it's OK to wait until needed for the sake of sanity. But I want to emphasize this again... if you have high prolactin and/or lactating, it's a near 100% confirmation that you failed to control your estrogen levels.

    How To Control Prolactin

    To control prolactin, or elevated prolactin, we use drugs that activate dopamine. Dopamine is a chemical launched by cells in the brain with the purpose of signaling nerve cells. So these drugs we're looking at are dopamine agonists. There are several things that affect prolactin but dopamine is the dominant one that makes the overall difference.

    Dopamine works with the pituitary. They're friends, you see. But sometimes the pituitary gets a little excited and out of control, so Dopamine pays a visit to the pituitary and binds to the Dopamine receptors and slows prolactin production down to a reasonable level. This is all done with internal communication. What a nice friend to have. Make sense, folks? What a spectacular system we have. Even more reason to respect your body.

    Now that we know how prolactin elevates and how to fix the problem, let's have a look at common drugs used for prolactin control. I'm getting kind of bored with this article so I'll keep this short since I still have to cover progesterone.

    Common "Anti-Prolactin" (dopamine agonist) drugs available:

    - Pramipexole (Mirapex)
    - Cabergoline (Dostinex)
    - Bromocriptine (Parlodel)
    - Pergolide (Permax)

    Informative Data On Mentioned Inhibitors:

    *** Pramipexole (Mirapex)

    - Half Life: 8 hours
    - Recommended dose: 0.25 mg Every Night. Take right before you fall asleep. If after 3 days you can handle the dose just fine, increase to 0.5 mg. Then again to 0.75 and finally to 1 mg. Rarely more than 1 mg is needed.
    - Common side effects: Nausea, dizziness, vomiting, insomnia, constipation, confusion, visual disturbance, hallucinations, headaches, frequent urination, congestion, achiness.
    - Drug interactions: Do not use alongside other dopamine agonists. Avoid antihistamines altogether as the combination will have adverse effects on your central nervous system.

    *** Cabergoline(Dostinex)

    - Half Life: 65 hours
    - Recommended dose: 0.25 mg Every Third Day. If after 4 doses you feel good, increase to 0.5mg every third day.
    - Common side effects: Same as Prami for the most part, but can also cause anxiety and compulsive behavior.
    - Drug interactions: Avoid anorexiants (appetite suppressors) as the combo can cause severe levels of serotonin. also avoid other dopamine agonists. Avoid Codeine because the combination renders the drug ineffective and lowers blood pressure too much.

  5. #5
    clarky.'s Avatar
    clarky. is offline MONITOR
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    Sep 2012
    Caber could have been bunk as already said get some blood work and see how high it is then you will know how you will sort this.

    Oh and another thing have you got pre cycle bloods ?
    Last edited by clarky.; 01-20-2015 at 02:17 AM.

  6. #6
    J703 is offline New Member
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    Jan 2015
    Yes I have pre bloods.

    What panels do I get now??

    There is one for Prolactin, I will get.
    And the other Male Anti Aging, which covers CBC, Lipid, IGF-1, Thyroid, Estradiol Sensetive and Test.
    That should do it right??

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