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  1. #1
    MrFreshmaker's Avatar
    MrFreshmaker is offline Productive Member
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    Does exogenous HGH suppress natural production?

    According to the blood test i did a while back,IGF-1 and IGFBP-3 levels are very low,and a friend of mine owns a pharmacy,so he is willing to give me HGH without prescription.But i was wondering does it suppress natural production of HGH or does it affects testosterone or any other hormone in any way?I did some research,but i read conflicting reports,some say it will suppress your natural HGH production to some degree,but not other hormones,and others say prolonged use will suppress natural production permanently,even testosterone!
    Can anyone clarify this for me please?

  2. #2
    Mr.BB's Avatar
    Mr.BB is offline Anabolic Member
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    It will not supress other hormones.

    It will supress some of the endocrine (central) gh release but not all, due to the pulsatile way it is released. It will not supress the paracrine (local) igf1 production.

  3. #3
    SOL!D5NAK3's Avatar
    SOL!D5NAK3 is offline Associate Member
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    It will. It has a short half life though. If you worry about your natural gh use it eod

  4. #4
    MrFreshmaker's Avatar
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    Thanks for reply guys.
    What about the doses? 4iu eod?

  5. #5
    SOL!D5NAK3's Avatar
    SOL!D5NAK3 is offline Associate Member
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    Quote Originally Posted by MrFreshmaker
    Thanks for reply guys. What about the doses? 4iu eod?
    Depends on your goals, but that is a regular dose.
    There are different methods . I would use it at 4iu eod before bed (mostly for fat burning and contest prep ) though i have not YET used it.

  6. #6
    magic32's Avatar
    magic32 is offline AR-Elite Hall of Famer
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    Yes, because hGH participates in the negative feedback loop.

    In an optimally functioning system, the body's negative feedback loop routinely measures the levels of participating substances. This measurement determines the continued production and secretion to varying degrees (same, more, less, none - shut down) of said substances based on it's specific/direct and interrelated/indirect functions.
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