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  1. #1
    zenvost1 is offline Associate Member
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    which proton pump inhibitor doesn't cause gyno?

    I used proton pump inhibitor in the past but caused gyno to me it was rabeprazole I want to use ppi again but which one doesn't cause gyno? I appreciate any help. Thank you

  2. #2
    Lemonada8's Avatar
    Lemonada8 is offline Knowledgeable Member
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    a PPI caused gyno? never heard of that.

    try nexium, or protonix

  3. #3
    zenvost1 is offline Associate Member
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    Quote Originally Posted by Lemonada8 View Post
    a PPI caused gyno? never heard of that.

    try nexium, or protonix
    Nexium is the Kong of ppi that cause gyno

  4. #4
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    hammerheart is offline Knowledgeable Member
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    Quote Originally Posted by zenvost1 View Post
    Nexium is the Kong of ppi that cause gyno
    What are you on? The only possible association that comes to my mind is the PPI inhibiting CYP3A4, but I'm taking and hard guess, and I doubt it can happen under physiological conditions.

    Ever tried ranitidine? It's not a PPI but can do the same through a different mechanism of action.

  5. #5
    zenvost1 is offline Associate Member
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    I used pariet rabeprazole and caused gyno so I just don't want to make it worser. Will check that ranitidine

  6. #6
    numbere is offline RETIRED- Knowledgeable member
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    Though rare all PPIs can cause gyno

    If rabeprazole gave you gyno they likey all will have the same effect.

    You can try taking a SERM such at nolva or ralox along with a PPI.

    You'd be better off making some adjustments to your diet and taking tums if you have an issue.

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