E2 too much low with 6,25mg/ED Aromasin. Need some good help.

Hello Guys, i've started my cycle since almost a week; Test E 250mg/w and Deca 500mg/w. I've started to take Aromasin 6.25mg/ED the day after the first Test E 250mg shot and i begin to felt the typical letargic state when E2 going lower; being i can check easily with a blood work as i'm friend of the Lab boss in front of my office, i did a E2 sensivity test; the result was: 0,20 pg/ml. If i do not take the Aromasin 6,25mg dose for some day, i begin to feel better ( i guess E2 begin to raise ). How could it be possible having E2 so low after few days just with a Test E 250mg shot ? Consider that i did several E2 test even off-cycle in the same lab for confirm and my it was around 27 pg/ml, and i felt better and strong. That is my good physiological level. Yesterday in the evening i did the second shot of Deca 250mg ( 4 days after the first Test E 250 shot) and i took 6,25mg Aromasin again; for all the evening i felt better without problem. Today, i felt letargic and with an "empty head".

Maybe it could be good to try to restart taking Aromasin 6,25mg/EOD even if now the hormones will increase in the blood stream, i think the thing should adjusting automatically keeping the dosage of 6,25mg/ED, as more androgens will be there accumulated for E2 conversion.

Some help and good tips, guys ?

Thanks !

How did you find e2 sensitive lab test in Italy???

Whats the exact name?

About your actual question (lol), if its not pharma (bought in pharmacy) it can be anything.

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Originally Posted by Mr.BB

How did you find e2 sensitive lab test in Italy???

Whats the exact name?

About your actual question (lol), if its not pharma (bought in pharmacy) it can be anything.

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I've bought it in a regular Pharmacy Mr.BB. Exclude a fake drug, it's authentic. What name do you want to know... the name of the E2 Test ? I don't know it... i could ask to my friend. But consider that if i do not take the AI, i felt better and my mood improving; when i did the E2 test off-cycle, my E2 was perfect in a good range.

Further info: months ago i had started to cycle but i have to interrupt the cycle for other reason; i had the same E2 problems/symptoms with Aromasin and i did the E2 test and it was 1.6 pg/ml.

So, it seems Aromasin, even at low dosage, cut down my E2 very strongly. I could try at another lab maybe to make a comparison....

Anyway, i don't need sensivity E2 Test to prove my E2 is too much low; a sensitivity E2 Test could be useful when light fluctuations ( around 3-7 points ) have to be meaningful. If in a specific Lab you test E2 when you're good, you can get that as reference value, and adjusting around it.

I find this whole situation very interesting. I'm a long time user of Aromasin and have had experience crashing my E2 down to zero.

This is another classic example of how an individual's genetics will determine the response to different compounds. Many years ago, I would take 25mg of aromasin per day on cycle, and I couldn't understand why I felt so terrible. I later found out that my E2 was crashed, and adjusted my dose to 12,5mg per day.

This is not a recommendation, but it just shows you how different people require different amounts of the same compound. There is no one size fits all. Find the dosage that works for you by observing blood work, and remember that it's unique to you.

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Originally Posted by Slacker78

Anyway, i don't need sensivity E2 Test to prove my E2 is too much low; a sensitivity E2 Test could be useful when light fluctuations ( around 3-7 points ) have to be meaningful. If in a specific Lab you test E2 when you're good, you can get that as reference value, and adjusting around it.

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Immunoassays are off up to 50-70%. I'd target E2 levels of at least 50 pg/ml.

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Originally Posted by Vash the Stampede

I find this whole situation very interesting. I'm a long time user of Aromasin and have had experience crashing my E2 down to zero.

This is another classic example of how an individual's genetics will determine the response to different compounds. Many years ago, I would take 25mg of aromasin per day on cycle, and I couldn't understand why I felt so terrible. I later found out that my E2 was crashed, and adjusted my dose to 12,5mg per day.

This is not a recommendation, but it just shows you how different people require different amounts of the same compound. There is no one size fits all. Find the dosage that works for you by observing blood work, and remember that it's unique to you.

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Yes Vash, i feel better now that i'm not the only one had crashed its E2 with Aromasin :D in that Lab, my good value is around 27.5pg/ml ( i checked it several times to confirm when i was off cycle ). What you told is very true: we have to find the dosage that fit for us. Yesterday morning when i did blood draw, my E2 was 0,20pg/ml; i didn't take Aromasin 6,25mg this time and in the evening, i did Deca 250mg and after 1 hour, i took Aromasin at the previous dosage; for all the evening and all the night, i hadn't no problem and felt well. This morning ( i didn't take still AI ) i wake up good but i begun slowly, during the day, to feel always more anxious and letargic with and "empty head"; i'm now on 500mg of total gear ( Test E 250mg + Deca 250mg ) and i don't if my feelings about now are due to low or high E2 raising; maybe the last Deca shot, raised E2 again and 6,25mg AI dosage is not more enough to keep it in control. But yesterday morning, my E2, it was so low... anyway, now i don't know if i should wait some day before take it again or take another 6,25mg regularly. I feel not good right now and i'm afraid to worse the situation if i take my AI 6,25mg dose...

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Originally Posted by bizzarro

Immunoassays are off up to 50-70%. I'd target E2 levels of at least 50 pg/ml.

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This^^^ - standard estradiol is measured for women... Hence we(males) need the sensitive essay....

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Originally Posted by NACH3

This^^^ - standard estradiol is measured for women... Hence we(males) need the sensitive essay....

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I don't know if where i live do the sensitive E2 essay; when i try to ask to them, they answer me that they don't know about if exists a E2 essay which could be more specific about it. If i don't find a lab which do this sensitive essay, won't i have no possibility to check E2 and adjusting the right dosage ? In past i used Adex 0,50/EOD and i always felt good; i didn't check E2, because i always felt very well. Now i trying to use Aromasin and adjusting dosages, but .... :(

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Originally Posted by bizzarro

Immunoassays are off up to 50-70%. I'd target E2 levels of at least 50 pg/ml.

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Were you ever able to find sensitive e2 test near you?

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Originally Posted by NACH3

This^^^ - standard estradiol is measured for women... Hence we(males) need the sensitive essay....

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Never found a local lab with sensitive e2 test available. Its just not possible here.

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Originally Posted by Mr.BB

Never found a local lab with sensitive e2 test available. Its just not possible here.

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Idem for me. How did you proceed in this case ? Did you perform the standard E2 test the same ?

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Originally Posted by Mr.BB

Were you ever able to find sensitive e2 test near you?

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Nope.

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Originally Posted by Slacker78

Idem for me. How did you proceed in this case ? Did you perform the standard E2 test the same ?

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Did the standard beta17 e2 estradiol in first few cycles, nowadays I dont do it so much. Results were not very consistent, most of the time got this:

http://forums.steroid.com/attachment...5&d=1473265460

Attachment 165315

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Originally Posted by Mr.BB

Did the standard beta17 e2 estradiol in first few cycles, nowadays I dont do it so much. Results were not very consistent, most of the time got this:

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Too much low. How did you feel when you did this blood work, and how much AI did you take ?

20pg/ml is in the lower range of normal for a sensitive e2 assay.

Some experience lethargy as a side effect when taking stane.

Just switch back to your normal dosage of dex for the remainder of the cycle.

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Originally Posted by numbere

20pg/ml is in the lower range of normal for a sensitive e2 assay.

Some experience lethargy as a side effect when taking stane.

Just switch back to your normal dosage of dex for the remainder of the cycle.

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Wait. It needs to know if lethargy is a Stane side effect or a low E2 side effect ?
Although it seems i didn't a sensitive E2 essay, the result was a low E2 anyway and it's compatible as i feel. Should i think E2 was in range, and the Lab result was totally incorrect and i'm experimenting just a Stane side effect ???? I'm a bit confusing if it's so...

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Originally Posted by Slacker78

Too much low. How did you feel when you did this blood work, and how much AI did you take ?

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This one and others with same values felt great. Actually never felt any low e2 symptoms, max AI used was on 0.5mg ed pharma anastrazole, which I use when on dbol.

Once got 70 pg/ml (first time on dbol), the bloating and water retention was obvious.

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Originally Posted by Slacker78

Wait. It needs to know if lethargy is a Stane side effect or a low E2 side effect ?
Although it seems i didn't a sensitive E2 essay, the result was a low E2 anyway and it's compatible as i feel. Should i think E2 was in range, and the Lab result was totally incorrect and i'm experimenting just a Stane side effect ???? I'm a bit confusing if it's so...

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I don't know what type of e2 assay you had completed.

If it was a sensitive assay, like is stated in the OP, then the result you got is okay.

Will you post your bw?

It's possible that your lethargy is a side effect from the AI and not low e2.

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Originally Posted by numbere

I don't know what type of e2 assay you had completed.

If it was a sensitive assay, like is stated in the OP, then the result you got is okay.

Will you post your bw?

It's possible that your lethargy is a side effect from the AI and not low e2.

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Yes, tomorrow i will post them. But i suspect that something is wrong. I'm now on total 500mg/week of gear, and it's impossible that just with 6.25mg/ED of Aromasin, i crash E2 to 0,20 pg/ml. Previous cycle, i used the same compound ( Test E 250/w and Deca 250/w) and dosages with Adex AI 0,50mg/EOD and i felt good.

Here is the previous E2 test i did a couple of months ago.

The Top is after 10 days i started the cycle with Test Prop 350mg/w with Aromasin 6,25mg/ED

The bottom is a month later, when i went off cycle; i have interrupted it after 15 days i begun because i had suddenly left for an holiday.

As you can see, there's a strange thing: the reference values on the right are pretty different in the two E2 Tests. They got E2 using two different procedure ? I don't know. But that is pretty strange and i suspect there's not full trust in this Lab.Attachment 165317

Here is another E2 essay i did some day after the previous one. It confirms the low E2 like yours, Mr. BB.

Gear: Test E 250mg/W - Deca 250mg/W ( i will increase Deca to 500mg/w next week )
AI: Aromasin before was 6,25mg/ED, now i increased it to 12,5mg/ED ( i feel better with the latter dosage ).

In someway or another one, several blood work shows that my E2 is low. I think that keeping 12,5mg/ED ( splitted in 2 6,25mg every 8-9 hours ) as i will inject on weekly base the gear, my E2 will increase automatically as accumulation phenomenon and i will keep it in control with this dosage.

I think Aromasin will be a mild AI ... but for someone, it's very strong.... as you can see. But i could suppose that being i'm using a long esters, i used it too much soon ( even 6,25mg/ED ) before estrogens conversion starting at all.

Attachment 165345