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Originally Posted by
DocToxin8
Your speculation is almost right on;
I've had gyno surgery before, but i never had gyno.
I just took the operation as a preventative measure as I thought;
Will I ever need to be able to grow titties? I decided I did not.
E2 needs to be kept in check for other reasons though,
for me it's mostly about water retention (cosmetic) or water retention (blood pressure) that's the issue with high levels of E2.
(Most of the time I can control this through diet though)
E2 being carcinogenic? Sure it is.
But to what degree?
We put postmeno. women on E even though it increases cancer risk,
simply because it makes them feel better. (Osteoporosis being a factor too)
I would speculate that E (in men) is most carcinogenic in breast tissue (like women, but I don't have those tissues),
and in the prostate. (Which I do have)
However, to all you,
Keep E2 in check, but if you're worried about cancer then I wouldn't use AAS either. Remember that cancer is an evolutionary process, where cells get mutations in their tumor suppressor genes like P53, and mutations that activate oncogenes.
Tumor supressor genes would normally kill the cell (apoptosis, suicide) when the DNA is damaged,
Oncogenes make the cell (and it's cell line; daughters) increase proliferation; cell division.
So when mutations in both are there you have a cell line that will replicate much faster AND accumulate DNA damage (since it doesn't kill itself)
However, this is still not a cancer cell, but the cell line will eventually give rise to it.
Still, one of the most important factors to prevent cancer (aside from strong carcinogens, like aflatoxin) is your own immune system.
Keep your immune system working,
and chances for cancer are much less.
(As a general rule)