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  1. #1
    MS_PHARM is online now New Member
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    Managing E2 during cycle on wet compounds

    Hey guys,

    I've done some cycles already, happy with the results. As a pharmacy student the majority of knowledge I have is based on medical evidence, so obviously some information (from BB's point of view) is lacking. The data I'm looking for today is about E2 managment during bulking phase on wet compunds.

    Let's look at a classical bulking cycle (with compounds belonging to each chemical group):
    600 mg of Testo Enan EW
    400 mg of Nandro Deca EW
    100 mg of Oxymeth ED

    From my perspective, the best way to approach the cycle is to front-load injectables and finish it with oral:
    1) if you front-load your injectables properly, just after few days you will reach your desired blood level of them,
    2) then you can find your AI & D2 agonist dosages,
    3) if you find your sweet-spot for E2 with given dosages of injectables during very first weeks of a cycle, rest of the cycle should be awesome (Oxymeth seems to be highly estrogenic while another wet compunds are out of control),
    4) assuming that the cycle would last 12 weeks, you'd break plateau of injectables with the oral in the 2/3-3/4 of the period.

    Now, I want to focus on AI dosage. It's known that narrow E2 blood-level range is crucial for male, both during a cycle and when T level is physiological. If you cut your E2 too much, forget about high intensity & volume workout, any libido and heavy gains. If you leave it too high, forget about the same & welcome fat accumulation (in a nutshell). As for me, when on TRT dosages of TE (120 mg/wk), my E2 must be within 24-28 pg/mL range to feel like I want. When on a cycle on wet compounds, the range can be moved SLIGHTLY higher (maybe to 32 pg/mL) so I can still have libido and no ED symptoms.

    The question comes in... What is your experience with E2 on wet compounds when bulking? Do you look for the highest E2 level which yet allows you to have pleasing sex like I do, just to profit from E2-mediated anabolic response w/o giving up sex-life? Or maybe you cut the level to physiological range (20-30 pg/mL)? Or just leave it as high as possible to get all the gains possible?

    Greets.

  2. #2
    MS_PHARM is online now New Member
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    waiting for your thoughts guys

  3. #3
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Not big on front-loading but to each his own. I'd simply run the cycle longer, maybe 14-16 weeks, especially if already on TRT.
    Not so easy front loading and trying to determine the need for a DA as it won't rise at the same rate estrogen will spike.
    E2 rising naturally plays a part in the rise of prolactin but it's not the only culprit. At 400 mgs deca I'd simply run caber at .25 x 2 per week to start and adjust as needed.
    E2 in most men on cycle is imho always better higher rather than lower. It allows for better IGF-1 levels thus better GH levels. I wouldn't put so much enphasis on a narrow range for E2.
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  4. #4
    i_SLAM_cougars's Avatar
    i_SLAM_cougars is offline Associate Member
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    Quote Originally Posted by MS_PHARM View Post
    Now, I want to focus on AI dosage. It's known that narrow E2 blood-level range is crucial for male, both during a cycle and when T level is physiological. If you cut your E2 too much, forget about high intensity & volume workout, any libido and heavy gains. If you leave it too high, forget about the same & welcome fat accumulation (in a nutshell). As for me, when on TRT dosages of TE (120 mg/wk), my E2 must be within 24-28 pg/mL range to feel like I want. When on a cycle on wet compounds, the range can be moved SLIGHTLY higher (maybe to 32 pg/mL) so I can still have libido and no ED symptoms.

    The question comes in... What is your experience with E2 on wet compounds when bulking? Do you look for the highest E2 level which yet allows you to have pleasing sex like I do, just to profit from E2-mediated anabolic response w/o giving up sex-life? Or maybe you cut the level to physiological range (20-30 pg/mL)? Or just leave it as high as possible to get all the gains possible?

    Greets.
    I’m a fan of low dose nolva during cycle, and not so AIs so much. I feel like to many people feel a twinge in their nipple, and freak out, jump the gun and start pounding arimidex by the gram, and it just ruins their cycle. Much better gains (at least in my experience) from letting the estrogen run a little high.

  5. #5
    Chicagotarsier is offline Senior Member
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    E2...in my opinion... Has ots bad sides. Your assumptions seem incomplete on multiple points. The one that really jumps out is you assume E2 is responsible for the sides you listed.

    I find no matter how you control E2 you take the same negative hits from prolactin. Libido is more tied to prolactin levels for..me than E2. Looking at just E2 is not realistic after week6 and really unrealistic after week 12.

    Also in reality HGH and insulin are always ran on cycle with AAS among middle up weightlifters and BB. HGH impacts prolactin even more than E2.

    My point is in the real world very few if any...other than aids patients...would fit your substance criteria for solid feedback. Prolactin control for libido is for me 5-7 times more important than E2 control.

  6. #6
    waltr64 is offline Junior Member
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    My doc tells me that there is a lot of individual differences in men and how much they convert Test to E. It also has a little to do with diet so make sure you get rid of all soy and other E causing foods if you are predisposed to high E. Currently I use amerdix at .25 eod and Proviron at 100mg per day and that seems to be good for me but you many only need half of that. My doc say's I am on the high end of Test to E conversion. Yes keep some caber on hand just in case, my friend had an issue and you don't want to have to wait 2 weeks to get it if you start having an issue. Good luck.

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