I have studied long and hard on this topic and hope I can find my answer here. On my precycle blood work my Estradiol level with the ultra-sensitive test was 36 (range being <29). So with that I started my Test cycle with .5mg Arimidex eod. After 5 weeks I started to feel a bit crabby, a little oily, and a tad bloated. I did my mid cycle blood work and my Estradiol came back at 48. Being deathly afraid of gyno I bumped my Adex to 1mg eod. In a week or so mood improved, oiliness decreased (slightly) and the water retention subsided. At this point I redid my blood work and Estradoil came back at 38. I know that Estrogen is a critical part of the muscle building process and a bit more is better than a bit less. My question is what is too high to which point gyno becomes a risk. What level is considered acceptable to run at. I know everyone is different but is 48 way too high? Is 38 too high? Any info would be greatly appreciated. Thank you.