Cialis, vasodilation v benefits of vasoconstriction

[Quester]

Ok, so the benefits of vasodilation include better delivery of nutrients to the muscle. And, the benefits of vasoconstriction include growth hormone and mTOR activity.
...issues that come to my mind based on my limited knowledge (maybe the answer is obvious and, / or, maybe their are many more questions about this that haven't yet come to me?

[Test Monsterone]

Weird that vasoconstriction (which means high blood pressure) equals more growth hormone. My IGF is like double a normal adult's and I have high blood pressure (controlled with medicine). I don't drink coffee before a workout or take any pre-workouts. I would stay away from vasoconstrictors entirely. If I want to feel like I'm going to die in the gym, I'll have some coffee a few hours before.

[fiddlesticks]

how do you figure vasoc = GH activity?

this could be true, amphetamines increase GH and are strong vasoconstrictors

ive also read cialis directly increases androgen receptors which is amazing..

in my own experience cialis drastically improves my performance and results in far better gains, not just bloodflow but respiration as well, Its definitely worth using.

[Test Monsterone]

How much Cialis are we talking? How often and how long before a workout?

[Quester]

Fiddle,
Can you provide some direction for me to evaluate and come to the decisions you have made, please.

[KennyJ]

Fiddle,
Can you provide some direction for me to evaluate and come to the decisions you have made, please.

https://tenor.com/view/chair-gif-9751403

[fiddlesticks]

Fiddle,
Can you provide some direction for me to evaluate and come to the decisions you have made, please.

for what? It's pretty well documented amphetamines and similar drugs like bupropion have effects on raising GH.

Here is a useful bit I found.

Significant reductions in somatostatin and neuropeptide Y release coincided with increased dopamine release, suggesting that dopamine has an inhibitory effect on the release of both peptides.

[Quester]

I should have written that blood flow restriction increases mTOR and growth hormone.

[Proximal]

Ok, so the benefits of vasodilation include better delivery of nutrients to the muscle. And, the benefits of vasoconstriction include growth hormone and mTOR activity.
...issues that come to my mind based on my limited knowledge (maybe the answer is obvious and, / or, maybe their are many more questions about this that haven't yet come to me?

Have a lull in class & am googling/searching this. Are you saying that the vasoconstriction itself or the contributors to vasoconstriction stimulate hgh? My searches are drawing blanks on both accounts.

[Quester]

I've been reading about it in Tnation. I guess Cialis doesn't matter to "Blood Flow Restriction" training because the principles are to allow blood to flow into the muscle, arterial, but to occlude outflow, venous.
This is a link to one of the articles
https://www.t-nation.com/training/bl...ction-training
there are more links provided by putting "Blood Fl..." into the search bar.

[almostgone]

Have a lull in class & am googling/searching this. Are you saying that the vasoconstriction itself or the contributors to vasoconstriction stimulate hgh? My searches are drawing blanks on both accounts.

I'm thinking there were several Japanese studies on the effects of vasoconstriction in regards to hypertrophy.
This isn't the one I'm thinking of, but section 5 of the abstract hints at it

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485988/

[Proximal]

I see. I'm seeing vasoconstriction differently than BFR, but see the direction that this is coming from. AG, thanks for giving me such an easily digestible bit of reading, lol, got to spend some time with this.

I was thinking that vasoconstriction typically is because of sympathetic activity and that maybe sympathetic activation was contributing to the bump in hgh.

TY guys, got some reading to do.

[almostgone]

I think there are a couple of more studies floating around, Prox.

Again, my memory is saying they were done in Japan, but I may well be wrong.

Also, try the terms in a search engine "blood flow occlusion and hypertrophy".

Hope that helps.


Edit: Sorry if I'm misunderstanding the intent of the thread, but that was what came to my mind.

Going to lay down for a while and hit the proparacaine eye drops. Some unnamed dumbass old fart may have slightly burned his eyes early today while welding up a mold for modification.

[fiddlesticks]

Afaik any form of hypoxia stimulates HIF which in turn stimulates GH production, one study i remember GH was elevated something like 350x from bfr

[KennyJ]

So in these studies, they are intentionally restricting blood flow while training to monitor effects?

[Proximal]

So in these studies, they are intentionally restricting blood flow while training to monitor effects?

Is it the wine, the hour or my age? But, are your cans getting bigger on your avi? Was that tank top stretched that much before? Good Lord, it's time for me to call it a day.

[KennyJ]

Is it the wine, the hour or my age? But, are your cans getting bigger on your avi? Was that tank top stretched that much before? Good Lord, it's time for me to call it a day.

LMAO, I zoomed it in a little Prox. You're not losing it. That's funny.

[fiddlesticks]

So in these studies, they are intentionally restricting blood flow while training to monitor effects?

thats the whole purpose yes, lots of interesting effects happen like lactic acid sits around longer than normal, gh skyrockets to absurd levels and generally the muscle is under an oxygen deficit much more severly than usual

i can't see GH levels rising 300x+ being a healthy thing... Even the most intense natural training regimen can't expect more than a 50x boost and that is under absolutely near-death conditions...(fasting, extreme heat, dehydration)

[Quester]

I think the concept has its origin in "the pump." Blood flow occlusion has many methods, tying your arm like the Ultimate Warrior

(AWESOME!), do drop sets, isometrics etc... The studies probably use a more direct approach so as not to create and argument for their opposition but it is all about blood not being able to leave the the muscle. I was confused in that I thought it was about blood not leaving or entering.