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Thread: Test C compound with an AI

  1. #1
    Rkinney2004 is offline New Member
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    Test C compound with an AI

    Has anyone here ever gotten Testosterone cypionate infused with an AI (anastrozole)? This is from a TRT clinic and according to the doctor they do that to eliminate having to take an oral every day. Doc said if additional AI's are needed on top of the Test C/AI then he/she will provide it via tablet.

  2. #2
    Gallowmere's Avatar
    Gallowmere is offline Knowledgeable Member
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    That sounds like a recipe for fucking disaster. You may not need the AI, and since your whole test source is now contaminated with it, you’re not gonna be able to remove it to troubleshoot.

    I’d seriously recommend seeing if you can get some TestE or C with no bullshit added, in case the AI crashes your E2 and/or tanks your lipids.
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  3. #3
    Rkinney2004 is offline New Member
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    Quote Originally Posted by Gallowmere View Post
    That sounds like a recipe for fucking disaster. You may not need the AI, and since your whole test source is now contaminated with it, you’re not gonna be able to remove it to troubleshoot.

    I’d seriously recommend seeing if you can get some TestE or C with no bullshit added, in case the AI crashes your E2 and/or tanks your lipids.
    It may be because my bloodwork. The labs showed that my Estradiol level is at 90.7, normal range should be between 7.6 - 42.6 and Testosterone level is also on the high end at 1500. So it may just be a temporary thing so I hope.

    My TRT routine...should I choose to accept...see below ( I have not started yet ).

    THREE weekly injections:

    • ONE testosterone cypionate injection *This has the estrogen blocker (anastrozole) infused*

    • TWO HCG injections at 500 IU.

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    The God Himself's Avatar
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    Quote Originally Posted by Rkinney2004 View Post
    It may be because my bloodwork. The labs showed that my Estradiol level is at 90.7, normal range should be between 7.6 - 42.6 and Testosterone level is also on the high end at 1500. So it may just be a temporary thing so I hope.

    My TRT routine...should I choose to accept...see below ( I have not started yet ).

    THREE weekly injections:

    • ONE testosterone cypionate injection *This has the estrogen blocker (anastrozole) infused*

    • TWO HCG injections at 500 IU.
    I would just lower the hcg and go with sole test e (without an AI infusion). If you dont want kids you can drop hcg altogether imo

  5. #5
    Rkinney2004 is offline New Member
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    Well I dont exactly know if I have a choice. I know I can express my opinion which I did today so I'm just waiting for a call back. As far as kids go, I am happy with the 2 I have + a vasectomy 3 yrs ago.

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    JaneDoe is offline Banned
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    One correction; Anastrozole is not an estrogen blocker! It is an inhibitor. In other words, it lowers serum estrogen levels in the body - inhibiting the aromatase enzyme!
    If it were you would just run Nolvadex 10 mg day
    Nolvadex unlike anastrozole will block estrogen receptors instead of inhibiting it

  7. #7
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    Quote Originally Posted by Rkinney2004 View Post
    It may be because my bloodwork. The labs showed that my Estradiol level is at 90.7, normal range should be between 7.6 - 42.6 and Testosterone level is also on the high end at 1500. So it may just be a temporary thing so I hope.

    My TRT routine...should I choose to accept...see below ( I have not started yet ).

    THREE weekly injections:

    • ONE testosterone cypionate injection *This has the estrogen blocker (anastrozole) infused*

    • TWO HCG injections at 500 IU.

    Are you noticing any negatives from your high E? So much of E2 management is symptom related. Bloodwork obviously helps, but I run on the high end (similar to your levels) and have never had to use an AI ever and I’m doc prescribed test. Even when I run blasts, I don’t run an AI. Some are just more susceptible. Are you gyno prone or ever had it as a kid? Any libido, ED, fatigue or crying at hallmark movies?

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    Gallowmere's Avatar
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    Quote Originally Posted by SampsonandDelilah View Post
    Are you noticing any negatives from your high E? So much of E2 management is symptom related. Bloodwork obviously helps, but I run on the high end (similar to your levels) and have never had to use an AI ever and I’m doc prescribed test. Even when I run blasts, I don’t run an AI. Some are just more susceptible. Are you gyno prone or ever had it as a kid? Any libido, ED, fatigue or crying at hallmark movies?
    I would add in bloating and problematic blood pressure to the symptoms to pay attention to.

    Other than that, this is spot on. Everyone in different in how much they aromatize and how it affects them overall. On the opposite end to OP, even when my total levels are in my TRT range, I only hit around 20-23 E2, and on a 600mg cycle, I was still only in the high 60s.

    For some guys, being in the 40s causes the symptoms mentioned in my post and the one previous. For others, they can run up into the 200+ range and never have problems. This is why treating based solely on labs is a terrible idea. The hormone ranges are completely useless once you go population wide. They’re an average. And I’m not sure about you, but I’ve never met this “average person”. The bell curve for the ranges are absurdly small and keep trending downward for some weird ass reason.

    A few years back, 1200 total would have been the high end of normal. Now it’s suddenly too high because lab values have been shifted down, likely to be more “average” in a world full of hypogonadal men.

  9. #9
    balance is online now Associate Member
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    Quote Originally Posted by Rkinney2004 View Post
    Has anyone here ever gotten Testosterone cypionate infused with an AI (anastrozole)? This is from a TRT clinic and according to the doctor they do that to eliminate having to take an oral every day. Doc said if additional AI's are needed on top of the Test C/AI then he/she will provide it via tablet.
    Sounds like my first trt clinic lol. I bet I can name the compounding pharmacy you receive from too. I’ll even go one further and bet your test C RX is prescribed at 200mg test C and 1mg anastrozol per ml. I left that clinic for the exact reason that they would not prescribe straight test C and deal with an ai separately, which a much better and likely optimized trt approach. There are way too many good clinic choices out there to have to be tied to this sort of protocol.


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  10. #10
    Rkinney2004 is offline New Member
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    I haven't started the TRT yet. I have been self administering TEST for 8 weeks now and between weeks 4 and 5 is when I started to notice my nipples were getting a bit tender and sensitive. I took 50mg of clomid everyday or 5 days and everything went back to normal and has been sense. Never had gyno however, running 400mg of Test C per week not only caused my tender nipples (especially at the gym) but it also had some negative effects on my sex drive/libido.

  11. #11
    balance is online now Associate Member
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    Test C compound with an AI

    Quote Originally Posted by Rkinney2004 View Post
    I haven't started the TRT yet. I have been self administering TEST for 8 weeks now and between weeks 4 and 5 is when I started to notice my nipples were getting a bit tender and sensitive. I took 50mg of clomid everyday or 5 days and everything went back to normal and has been sense. Never had gyno however, running 400mg of Test C per week not only caused my tender nipples (especially at the gym) but it also had some negative effects on my sex drive/libido.
    To be clear 400mg is outside of what is medically considered trt. If you ran labs as you mentioned and total t was around 1500 and your estrogen was high that is all to be expected for running that amount of test. Your follow up posts to this thread have made your question/point unintelligible? If you have another question state it clearly. The answer to your original question though is No that is far from an ideal trt protocol.


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  12. #12
    Windex is offline Staff ~ HRT Optimization Specialist
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    Find a new place. AI infused Test is a terrible idea
    I no longer check my inbox. If you PM me I will not reply.

  13. #13
    Rkinney2004 is offline New Member
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    Quote Originally Posted by balance View Post
    To be clear 400mg is outside of what is medically considered trt. If you ran labs as you mentioned and total t was around 1500 and your estrogen was high that is all to be expected for running that amount of test. Your follow up posts to this thread have made your question/point unintelligible? If you have another question state it clearly. The answer to your original question though is No that is far from an ideal trt protocol.


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    I started a cycle at 400mg and near end is when I started looking in to TRT, that's why my levels were high. I was just asking about the Test infusion because I have never heard of it before. As for the follow up posts, I was answering questions that were asked.

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    GearHeaded is offline BANNED
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    Quote Originally Posted by Rkinney2004 View Post
    I started a cycle at 400mg and near end is when I started looking in to TRT, that's why my levels were high. .
    your estrogen levels were NOT high. the range you were looking at was for "normal" ,, ie, regular guys with normal testosterone production ,, not guys blasting 400mg of exogenous test. for blasting 400mg of test, your E2 level of 90 wasn't even high for that amount of test

    AI infused test is a terrible idea, as mentioned already
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    Ashop's Avatar
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    Quote Originally Posted by Rkinney2004 View Post
    Has anyone here ever gotten Testosterone cypionate infused with an AI (anastrozole)? This is from a TRT clinic and according to the doctor they do that to eliminate having to take an oral every day. Doc said if additional AI's are needed on top of the Test C/AI then he/she will provide it via tablet.
    That's a new one on me. Never heard of anything like that myself.

  16. #16
    balance is online now Associate Member
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    Test C compound with an AI

    Quote Originally Posted by Ashop View Post
    That's a new one on me. Never heard of anything like that myself.
    It’s quite common with many trt clinics from what I have seen. I believe there is a large compounding pharmacy many of these clinics use and that pharmacy must push it pretty hard. Why? Who knows but my guess it’s easier and cheaper for them.

    As I mentioned previously I think it’s a terrible rx for many reasons.

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