
Originally Posted by
Quester
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I know something...
Metaprolol also has a chronotropic and ionotropic effects, it slows down rate and ejection force (amount of blood pumped with each contraction as measured in the left ventricle. While atenolol and Metaprolol are of the same class, non-selective B1, one has more effects than the other.
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Beta blockers:
I gotta research but I think I remember that one of their effects can be described as neural because they tone down the intensity. I don't have the right words for it but essentially, mitigates sympathetic nervous activation (fight-flight response) in the cardiovascular system. Vasodilation, rate, ejection force, are the general targets but they do it by blocking activation originating in the brain. So, gather the epinepherine, nro-epi and other stress hormones are the target in order to block their activation in the cardiovascular.
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When I worry about taking them, I'm thinking of lower heartbeat moving less blood causing less O2 to get to the tissues. If however, I could avoid that and just have less INTENSITY (less reactivity to the environment and less ARRRGGGHHHHH!!! -type negativity.