Androgenconstruction predicts which steroids in theory go well with each other!
The science behind Stacking Multiple steroids!
The German Scientist used Genetically Manipulated Hamstercells which therefore produced androgen-receptors, they were able to see what happened through promotors and labeled proteins.
They used a variety of different promotors to ensure accurate testing!
They used MMTV, (ARE)2TATA en GRE-OCT binded to a plasmide-ring to get them in the cells and then exposed the cell to different concentrations of all sorts of compounds (AS and Prohormones!).
The results were calculated by the computer and they programmed it to divide the compounds and classes...
used compounds:
Precursors:
DHEA
Androstenedione
Naturally Occuring:
Testosterone
DHT
Nandrolone
Rest:
Stanozolol (Winstrol)
Oxandrolone (Anavar)
R1881
Good combos according to research:
Testosterone/Oxandrolone
Testosterone/Stanzolol
Testosterone/Androstenedione
Nandrolone/Oxandrolone
Nandrolone/Stanzolol
Bad combos:
Testosterone/Nandrolone (!!!!)
Oxandrolone/Stanzolol
Offcourse this isn't 100% what would happen in Human cells but still it is much more accurate than just to see which steroid has the most affinity for the Androgen Receptor (since this includes the entire chain of processes).
Greets
Kingofmasters
Complete article!
Holterhus PM, Piefke S, Hiort O. Anabolic steroids, testosterone-precursors and virilizing androgens induce distinct activation profiles of androgen responsive promoter constructs. J Steroid Biochem Mol Biol. 2002 Nov;82(4-5):269-75.
BTW:
R1881 = Methyltrienolone (the very toxic oral Trenbolone!)
Attachment:
The Scheme that predicts which compounds go well with each other!
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