what can supress igf-1 during pct (letro)

[dogfight]

do you know if letro will supress your igf-1 levels? of any other anti -estrogens can any thing elese?

[JohnnyB]

Yes it will as with all drugs that are made for breat cancer

JohnnyB

[Slic4788]

Not letro but nolva, yes.

[HumanPerfection1]

nolva deff

[rodge]

letro and aromasin are actually raising igf-1 levels.

-rodge

[dogfight]

ok so thats the good thing about it but i dont understand if letro is a anti-aromatise why is there a rebound affect? an if i take Ldex to fight the rebound will that lower my igf-1 or just not affect it??
thanx all!!

[reveremuscle]

Going to start IGF tuesday, last dose of 50mg clomid was friday, should I be all set?

[Slic4788]

ok so thats the good thing about it but i dont understand if letro is a anti-aromatise why is there a rebound affect? an if i take Ldex to fight the rebound will that lower my igf-1 or just not affect it??
thanx all!!

taper off the letro slowly to avoid the rebound effect.

[supersteve]

There's really no consensus either way.
In one study letro raised igf-1 (older women) and in another (teenage boys) it was lowered slightly.
Arimidex also shows conflicting results.

Tamoxifen certainly seems to lower igf-1. But it does this by suppressing your endogenous GH release. So if you're injecting GH this really isn't of any concern.