Can anyone here actually tell a difference when taking grapefruit juice with orals?

[EmptyWallet]

Can anyone here actually tell a difference when taking grapefruit juice with orals? I mean hell I'll do it if someone can actually say they see it works but I'm low carbing now and I dont want to jack that up with the grapefruit juice, or actually, would the grapefruit juice have a signifigant impact on my carbs? Hell, someone steer me in the right direction here.....

[bigkev]

grapefruit juice? thats a new one on me.

[Billmister]

bump

[SUPERDAVE]

bump

[holly]

I think I know what empty is referring to - grapefruit juice contains something called narginen (spelling may be incorrect) which is proported to increase the efficiacy of certain drugs.

Not a juicer myself though (yet) so cannot help you from firsthand knowledge.

Was interested so I did a search - found this:

Narginen – flavonoid high in grapefruit juice; inhibits first-pass metabolism of many drugs detoxified through the Cyp3A4 enzyme-antiporter system in the intestine (tips of villi).

Seems relevant, don't understand what the implications are though.

[EmptyWallet]

Originally posted by holly
I think I know what empty is referring to - grapefruit juice contains something called narginen (spelling may be incorrect) which is proported to increase the efficiacy of certain drugs.

Not a juicer myself though (yet) so cannot help you from firsthand knowledge.

Exactly, people over at elite (i know, i know) rave about it and at anabolicfitness.com as well. Utler flat out stated him self that it increases your blood levels up to 139 percent. I'll see if I can find some stuff on it to present to you guys.

[RiptUp]

I've heard it with all orals even prescription drugs. It increases the amount of the actual drug that is absorbed and used in the body. I take it with caffeine and ephedrine.

Ask a Dr. or pharmacist about it. It can be dangerous with certain prescriptiopn drugs.