i was under the impression that vitamin b6 should be run with tren but i found this:
Estrogen imbalance. Vitamin B6 reduces blood estrogen and increases progesterone. Therefore, a deficiency of Vitamin B6 can cause decreased liver metabolism of estrogen, further causing an excess of estrogen. This then results in "estrogen dominance". Yet another reason to take B6!
i also found a few others so now im not so sure.