Block Sex horomone binding globulin????

[Rookie1974]

Any one know how to block sex horomone binding globulin???? Or is their someting that will bind to it thereby creating a inhibition like effect???

[Hard Head]

tongkat ali

[Swifto]

I'm not aware of any compounds that will actually block it...?

Proviron has one of, if not the, highest binding affinity to SHBG so its a wise choice here, considering its availability and price. Its easily accessable to me and has other qualities than binding to SHBG. Another compound that binds to SHBG well is Anavar. But not nealry as well as Proviron.

[SPIKE]

Proviron has one of, if not the, highest binding affinity to SHBG so its a wise choice here, considering its availability and price.

Have to agree with Swifto here, Proviron would be your best choice for this sole purpose.

[Swifto]

Have to agree with Swifto here, Proviron would be your best choice for this sole purpose.

Its an intresting topic of being able to "block" SHBG.

[BajanBastard]

IMO blocking SHBG will lead to higher bio-availability of the hormones being used but can increase the clearance rates of the hormone throwing off injection frequency for stable blood levels. Plus drugs like tren and trestolone that bind to SHBG very poorly don't need another drug to manage SHBG.

[Rookie1974]

Im not able to find the pharmacodynamics of Proviron. Im showing that an alternative name is Masterlone. Are their any other names for this compound? big k.l.g are tren and trestelone better compounds to use? Have you experiments with this technique? Am I right in thinking that bound test is not active but free test is and that as free test is eliminated, bound test is released from SHBG to become effective? What if I block with Proviron and lower the dose of test?

[chest6]

Im not able to find the pharmacodynamics of Proviron. Im showing that an alternative name is Masterlone. Are their any other names for this compound? big k.l.g are tren and trestelone better compounds to use? Have you experiments with this technique? Am I right in thinking that bound test is not active but free test is and that as free test is eliminated, bound test is released from SHBG to become effective? What if I block with Proviron and lower the dose of test?

Trestolone is some pretty harsh stuff..probably not ideal for this

[BajanBastard]

Trestolone is some pretty harsh stuff..probably not ideal for this

Where do you get this info Chest?

[chest6]

Where do you get this info Chest?

on paper at least..I hadn't heard of it til the last month or so

http://www.bodybuilding.com/fun/catment.htm

[BajanBastard]

on paper at least..I hadn't heard of it til the last month or so

http://www.bodybuilding.com/fun/catment.htm

I wrote a long ass profile on it a few months back. Yeah it's a strong drug up there with tren but i personally wouldn't say it's really 'harsh'. I was not saying he should use trestolone (cuz hell you can't get it), just used it as a ref to make my point. You're right though even if it were available it definitely won't be the ideal choice.

Now don't ever question me again!

[BajanBastard]

Im not able to find the pharmacodynamics of Proviron. Im showing that an alternative name is Masterlone. Are their any other names for this compound? big k.l.g are tren and trestelone better compounds to use? Have you experiments with this technique? Am I right in thinking that bound test is not active but free test is and that as free test is eliminated, bound test is released from SHBG to become effective? What if I block with Proviron and lower the dose of test?

Yeah you are. My line of thinking is a bit different from the conventional way though, IMO tren is the best compound for those who are not sensitive to it. Anyways back to SHBG as said before i personally believe it's a lil over hyped. Yes it binds to test making it inactive with the AR but it also keeps test in the system longer it also makes estrogen inactive (IMO i good thing). If you want to add the proviron with to a test cycle it can only help but don't expect it to turn the cycle into a super cycle just because it 'blocks' SHBG. BTW Trestolone is a super nandrolone like tren but IMO could be more anabolic and is only available in powder form for 30,000 U.S per kilo. If you're buying let me know

[powerliftmike]

Yeah you are. My line of thinking is a bit different from the conventional way though, IMO tren is the best compound for those who are not sensitive to it. Anyways back to SHBG as said before i personally believe it's a lil over hyped. Yes it binds to test making it inactive with the AR but it also keeps test in the system longer it also makes estrogen inactive (IMO i good thing). If you want to add the proviron with to a test cycle it can only help but don't expect it to turn the cycle into a super cycle just because it 'blocks' SHBG. BTW Trestolone is a super nandrolone like tren but IMO could be more anabolic and is only available in powder form for 30,000 U.S per kilo. If you're buying let me know

Yes. I dont know why you guys think SHBG is so evil. Pretty much every hormone has a binding protein. For example, alot of your cortisol is bound and thus unable to exert its effects. Taking andrognes ties up SHBG and I believe even lowers the availibility of it, so dont stress over it.

[BajanBastard]

Yes. I dont know why you guys think SHBG is so evil. Pretty much every hormone has a binding protein. For example, alot of your cortisol is bound and thus unable to exert its effects. Taking andrognes ties up SHBG and I believe even lowers the availibility of it, so dont stress over it.

I think the B.U.A.S.H.B.G (bodybuilders united against sex hormone binding globulin) movement started when Pinnacle theorized his gains on long cycle stopped because of it.

[SPIKE]

Taking andrognes ties up SHBG and I believe even lowers the availibility of it

You got it Mike. Androgens can lower and estrogen raise it. Actually quite a few things out there that can lower it. Seems the most common is Proviron and DHT derivatives though.

[Swifto]

Masterlone is Proviron.

[SPIKE]

Rookie, what are you exactly looking to do here? There is so much we can say but need to know exactly what you are looking to do here before we keep just throwing info out.

[neverenuff21]

yep, and this last post from iron didn't help it

[needbigguns]

dosent winny lower SHBG

[Swifto]

dosent winny lower SHBG

Yes. Its a DHT-Derivative as Jay stated.