i have a knot on my thigh bone after injection... it is now the 5th day and it hurts like hell (test cyp. and deca). used the right needle 1 1/2 on the glute, 22 gauge and new. also sterilize the shot area. my friend seems to think that its like that because i flinched while i was shot. the phone doctor said it might be an infection because it is swollen and it hurts when touch... mind you it is not at the injection point but at my thigh bone where it connects to the hip bone.... had some helpful answers on this site but i'm just specifying a little better. first timer by the way on my 4th week.