I am getting a little tenderness in my nipples and felt a small lump for the first time today. I still have 7 weeks left on my cycle with Test E and a couple of weeks left of Tren at 65 mg ED. The Test E I am running at 750 a week. I was going to start the letro I have. Was wondering how many squirts of the bottle I need to use ED. It doesn't say it on the bottle.