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Thread: Would a DHT inhibitor interfere with PCT? (read further...)

  1. #1
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    Would a DHT inhibitor interfere with PCT? (read further...)

    For my first cycle, I am considering the use of Testosterone Cypionate. I've also come to the conclusion that I will add a DHT inhibitor during the cycle in order to suppress the side effects such as excess oily skin, acne, potential hair loss, etc. I would in all probability go with Proscar as the DHT inhibitor.

    However, what I would be taking at the same time is Proviron. Proviron is a DHT derivative, and works as an aromatase-inhibitor. I'm wondering if the Proscar would interfere with the Proviron.

    But upon taking a look at the situation, i've realized that Proscar inhibits the 5a-reductase enzyme that turns testosterone into DHT. So upon ingestion of Proviron, it's already DHT. So therefore it doesn't need to interact with the 5a-reductase enzyme (which Proscar inhibits).

    Did I just answer this question myself?? lol.

    Anyhow, even though i've determined that Proviron doesn't need to interact with 5a-reductase, i'm still wondering if Proscar would interfere with it.

  2. #2
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    Bump...

  3. #3
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    Bump again... still no responses! Or maybe that's because I already answered the question myself, lol.

  4. #4
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    proscar wont interfer with it, and for the exact reason you said...its already reduced so it cant be affected. Same holds true with anadrol, masteron, winny, anavar, etc. DHT derived steroids will remain unchanged by 5 alpha reductase inhibitors. Only ones that can reduce like test , bold, nand, will it affect.
    as far as affecting your PCT, its shouldnt hurt either as DHT seems to inhibit the HPTA, and its reduction seems to keep LH elevated

  5. #5
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    Excellent, thanks for the reply. Although I just thought of something... since Proviron is a DHT derivative, won't that keep shutting down my natural testosterone production? Because of that, it sounds like as an aromatase-inhibitor, it's good. But for PCT, not so much...

    Unless i'm wrong...???

  6. #6
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    for whatever reason, proviron doesnt seem to inhibit the HPTA that much, neither does var, but i would not run iether IMO.
    Its hard to say how inhibitory DHT is to the HPTA. The thing is, DHT blocks estrogen, which is why some ppl put on weight and get gyno after starting proscar/propecia. It is well known that estrogen is very inhibitory to the HPTA. So which is more? or are they the same at ihibiting? This they may never know. I would assume estrogen is more inhibitory than DHT. However, squashing them both with proscar and a aromasin or letro, you would think a larger rise in testosterone would be expected. Who knows?
    All i know is im gonna try an experiment this year with arimidex and propecia both at 1mg a day for a month or so...then test my testosterone. And of course id test right before as well. Then i d take a break for awhile.
    Then id take it a step further and run dutasteride and letro for a month or so. I suspect a bigger increase with duta and letro, though im sure my sex drive will be in the shitter,lol.
    Ill probably need like 5 blood tests for this whole damn thing. Anyway, just thoutght id share that.

  7. #7
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    Interesting, though Proviron has been used as a PCT by many bodybuilders, so i'm sure its shutdown of HPTA isn't big if anything at all.

  8. #8
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    yeah, try it. besisdes i think proviron is less androgenic than your own DHT. So nanogram for nangram it may have a less inhibitory effect on HPTA

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