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Thread: Cyogenx question

  1. #1

    Cyogenx question

    i have Cyogenx for my pct following a mass tabs cycle that i'm starting on july 1st. i've read people saying they are also taking it during cycle. i thought that would be a bad idea because although it combats estrogen...it boosts natty test.

    what do you think

    thanks

    82

  2. #2
    bump

  3. #3
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    mostly everything that combats estrogen boosts natty test, not just Cyogenx

  4. #4
    yea i understand but what i was asking was that i have read that it is a bad idea to take natty test boosters when taking a ph or aas

  5. #5
    during cycle that is

  6. #6
    I think the idea is that you wouldn't bother taking natural test boosters during a cycle because it's not going to maximize their test boosting ability, and it's counter productive. The idea behind CyoGenX is to lower estrogen, which has the additional effect of boosting test...but that's not why you're taking it. Does that make sense?

    Plus...one of the ingredients in CyoGenX will lower SHBG and allow any steroids or whatever to remain unbound and free to do their job. It works "with" steroids, PHs, and test boosters, not against them. That's what I designed it for.
    Last edited by Property of Steroid.com; 06-23-2007 at 05:30 AM.

  7. #7
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    CyoGenX can be a useful tool in addition to tried and true PCT components, but I certainly would not waste my money on it to use it in conjunction with a cycle unless your cycle consists of OTC products (mass tabs) to begin with.

  8. #8
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    Quote Originally Posted by EliteSniper
    CyoGenX can be a useful tool in addition to tried and true PCT components, but I certainly would not waste my money on it to use it in conjunction with a cycle unless your cycle consists of OTC products (mass tabs) to begin with.
    Based on what I've read I'm actually thinking of running it during my next cycle, could help and I don't care about the money if it doesn't. Thinking of running Cyogenx during cycle and both Cyogenx and Myogenx during pct.

  9. #9
    Quote Originally Posted by EliteSniper
    CyoGenX can be a useful tool in addition to tried and true PCT components, but I certainly would not waste my money on it to use it in conjunction with a cycle unless your cycle consists of OTC products (mass tabs) to begin with.
    The scientists who studied the primary ingredient in CyoGenX compared it (in efficiency) to Letrozole. I don't think that's a waste of money....

    I use CyoGenX right now as my only AI.

  10. #10
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    Anthony Roberts, what is the primary ingredient? I would like to look into this product(s) in greater detail. I've heard mixed reviews, but science could prove things elsewise, eh?

    Thanks for any response as I'm sure you are a busy man.

  11. #11
    Quote Originally Posted by EliteSniper
    Anthony Roberts, what is the primary ingredient? I would like to look into this product(s) in greater detail. I've heard mixed reviews, but science could prove things elsewise, eh?

    Thanks for any response as I'm sure you are a busy man.
    The primary ingredient is procyanidin, the others are resveratrol and urtica diocia. Here's what they all do:

    • Procyanidin:



      Inhibits the Aromatase Enzyme (prevents testosterone from converting to estrogen at the genetic level, preventing both transcription and expression of Aromatase) [1-4] .
      Acts similarly to Letrozole (a prescription Aromatase Inhibitor), and can destroy breast tumor tissue (gynecomastia) [1].
      Has anabolic properties (Inhibits the Glucocorticoid Receptor, thus allowing more muscle to be built)[4].
      Has Anti-Hypertensive properties [5].
      Improves Cognitive Function [5].
      Lowers LDL Cholesterol [6].
      Is a strong Anti-Oxidant (stronger than vitamin C or E) [6]



      Resveratrol:
      Is a mixed estrogen receptor Agonist/Antagonist [7] .
      Acts similarly to Nolvadex (a prescription Selective Estrogen Receptor Modulator) [7] .
      Acts Similarly to both Arimidex (a competitive Aromatase Inhibitor) as well as Aromasin (a noncompetitive Aromatase Inhibitor) [8].
      Is Anti-Arthritic [9-10] Is Cardioprotective [11-12].
      Has anti-inflamatory properties [13-15].
      Aids in Fat loss [16-17] Increases lh - leutenizing hormone - and FSH - follicle stimulating hormone - [18].
      Protects the liver [19-20].
      Is an Anti-Viral [15, 21-22]
      Protects against prostate cancer [23-28]


      Urtica Dioica:
      Is a potent Aromatase Inhibitor [29] .
      Acts similarly to Proviron (a prescription anabolic steroid) in binding to Sex Hormone Binding Globulin, thus making more testosterone "free" and biologically active [30-31] .
      Can reduce size of Benign Prostate growth [30]. Improves HDL/LDL cholesterol ratio [32-33]



      References:

      1. Grape seed extract is an aromatase inhibitor and a suppressor of aromatase expression. Cancer Res. 2006 Jun 1;66(11):5960-7.

      2. Suppression of Estrogen biosynthesis by procyanidin dimmers in red wine and grape seeds. Cancer Res. 2003 Dec 1;63(23):8516-22.

      3. Suppression of aromatase (estrogen synthetase) by red wine phytochemicals. Breast Cancer Res. Treat., 67: 133-146, 2001

      4. Modulation of aromatase gene expression by grape seed extract. Io Kijima, et al. City of Hope, Durante, CA.

      5. Antihypertensive and cognitive effects of grape polyphenols in estrogen-***leted, female, spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2005 Sep;289(3):R771-5.

      6. Concentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjects. Am J Clin Nutr. 2006 Jul;84(1):252-62.Am J Clin Nutr. 2006 Jul;84(1):252-62.

      7. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta.Endocrinology. 2000 Oct;141(10):3657-67.

      8. The red wine polyphenol resveratrol displays bilevel inhibition on aromatase in breast cancer cells. Toxicol Sci. 2006 Jul;92(1):71-7. Epub 2006 Apr 11.

      9. Effects of resveratrol in inflammatory arthritis.Inflammation. 2007 Apr;30(1-2):1-6.

      10. [Inhibitory effect of resveratrol on the proliferation of synoviocytes in rheumatoid arthritis and its mechanism in vitro] Zhong Deca-Durabolin - nandrolone decanoate - Da Xue Xue Bao Yi Xue Ban. 2006 Aug;31(4):528-33. Chinese.

      11. Resveratrol ameliorates experimental autoimmune myocarditis. Circ J. 2007 Mar;71(3):397-404

      12. Resveratrol Increases Vascular Oxidative Stress Resistance.Am J Physiol Heart Circ Physiol. 2007 Jan 12; [Epub ahead of print]

      13. [Biological effects of resveratrol and other constituents of wine] Ceska Slov Farm. 2003 Nov;52(6):272-81. Review. Czech.

      14. Polyphenolic phytochemicals versus non-steroidal anti-inflammatory drugs: which are better cancer chemopreventive agents? J Chemother. 2004 Nov;16 Suppl 4:3-6. Review.

      15. Biological effects of resveratrol. Antioxid Redox Signal. 2001 Dec;3(6):1041-64. Review.

      16. Borra MT, Smith BC, Denu JM. "Mechanism of human SIRT1 activation by resveratrol." J Biol Chem. 2005 Apr 29;280(17):17187-95.

      17. Picard F, et al. "Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma." Nature. 2004 Jun 17;429(6993):771-6.

      18. Juan ME, et al. "trans-Resveratrol, a natural antioxidant from grapes, Increases sperm output in healthy rats." J Nutr. 2005 Apr;135(4):757-60.

      19. Kasdallah-Grissa A, et al. "Protective effect of resveratrol on ethanol-induced lipid peroxidation in rats." Alcohol Alcohol. 2006 May-Jun;41(3):236-9

      20. Sener G, et al. "Protective effects of resveratrol against acetaminophen-induced toxicity in mice." Hepatol Res. 2006 Apr 1; E-Published Ahead of Print

      21. Effect of resveratrol on herpes simplex virus vaginal infection in the mouse. Antiviral Res. 2005 Sep;67(3):155-62.

      22. 3,4',5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cyt*****lovirus replication and virus-induced cellular signaling. Antiviral Res. 2004 Aug;63(2):85-95.

      23. Yoo KM, et al. "Potent Inhibitory Effects of Resveratrol Derivatives on Progression of Prostate Cancer Cells." Arch Pharm (Weinheim). 2006 Apr 18;339(5):238-241

      24. Jones SB, et al. "Resveratrol-induced gene expression profiles in human prostate cancer cells." Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):596-604.

      25. Scifo C, et al. "Resveratrol and propolis as necrosis or apoptosis inducers in human prostate carcinoma cells." Oncol Res.2004;14(9):415-26.

      26. Kim YA, et al. "Antiproliferative effect of resveratrol in human prostate carcinoma cells." J Med Food. 2003 Winter;6(4):273-80.

      27. Stewart JR, Artime MC, O'Brian CA. "Resveratrol: a candidate nutritional substance for prostate cancer prevention." J Nutr. 2003 Jul;133(7 Suppl):2440S-2443S.

      28. Ratan HL, et al. "Resveratrol - a prostate cancer chemopreventive agent?" Urol Oncol. 2002 Nov-Dec;7(6):223-7.

      29. Aromatase Inhibitors from Urtica dioica roots. Planta Med. 1995 Apr;61(2):138-140.

      30. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of sex hormone binding globulin with its receptor on human prostatic membranes.Planta Med. 1995 Feb;61(1):31-2.

      31. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (sex hormone binding globulin ).Planta Med. 1997 Dec;63(6):529-32.

      32. Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish folk medicine. J Ethnopharmacol. 2006 Oct 11;107(3):418-23. Epub 2006 Apr 15.

      33. Effect of Urtica dioica extract intake upon blood lipid profile in the rats. Fitoterapia. 2006 Apr;77(3):183-8. Epub 2006 Feb 23.

  12. #12
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    Thanks for the response.

    According to all this information, we can assume that CyoGenX should make ALL other PCT protocols obsolete, correct?

    So we can effectively and successfully make the "transition" during PCT with just the use of CyoGenX?

    If this is true, I'm on board.

  13. #13
    I will put Cyo + Myo PCT up against anything else out there, and say you can get (at least) similar/equal results as you can with pharmacuticals.

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