Whats the difference???

[cockMOTHAeffinDIESEL]

what is the difference in blocking the estrogen receptors and actually lowering the level of estrogen in your blood??
(For example:the diff in what letro does compared to what nolva does)

wouldnt it basically do the same thing?

[InsaneInTheMembrane]

nope, they're not the same

SERMS like nolvadex block the estrogen receptors in certain regions and triggers them in others...the systemic free estrogen usually accumulates and may surge pass baseline levels in some cases

AIs (like adex or letro) block the very enzymes that convert test to estrogen, as opposed to working on the receptors, thereby reducing systemic estrogen altogether. However, the aromatase enzymes can be re-activated once the AIs get flushed out of the system, which, as the enzymes continue to accumulate, can create an estrogen rebound effect when product is discontinued.

Suicide AIs (like aromasin) are kamikaze compounds that permanently bind and deactivate the aromatase enzyme, thereby not only reducing systemic estrogen but ensuring little or no estrogen rebound occurs when you discontinue using it. Your body has to produce new aromatase enzymes to replace the lost ones, not add to it.

[M302_Imola]

nope, they're not the same

SERMS like nolvadex block the estrogen receptors in certain regions and triggers them in others...the systemic free estrogen usually accumulates and may surge pass baseline levels in some cases

AIs (like adex or letro) block the very enzymes that convert test to estrogen, as opposed to working on the receptors, thereby reducing systemic estrogen altogether. However, the aromatase enzymes can be re-activated once the AIs get flushed out of the system, which, as the enzymes continue to accumulate, can create an estrogen rebound effect when product is discontinued.

Suicide AIs (like aromasin) are kamikaze compounds that permanently bind and deactivate the aromatase enzyme, thereby not only reducing systemic estrogen but ensuring little or no estrogen rebound occurs when you discontinue using it. Your body has to produce new aromatase enzymes to replace the lost ones, not add to it.

So...do you prefer aromasin over arimidex and letro due to its suicide aspects?

[Merc..]

nope, they're not the same

SERMS like nolvadex block the estrogen receptors in certain regions and triggers them in others...the systemic free estrogen usually accumulates and may surge pass baseline levels in some cases

AIs (like adex or letro) block the very enzymes that convert test to estrogen, as opposed to working on the receptors, thereby reducing systemic estrogen altogether. However, the aromatase enzymes can be re-activated once the AIs get flushed out of the system, which, as the enzymes continue to accumulate, can create an estrogen rebound effect when product is discontinued.

Suicide AIs (like aromasin) are kamikaze compounds that permanently bind and deactivate the aromatase enzyme, thereby not only reducing systemic estrogen but ensuring little or no estrogen rebound occurs when you discontinue using it. Your body has to produce new aromatase enzymes to replace the lost ones, not add to it.

Good post ....


Merc.

[cockMOTHAeffinDIESEL]

nope, they're not the same

SERMS like nolvadex block the estrogen receptors in certain regions and triggers them in others...the systemic free estrogen usually accumulates and may surge pass baseline levels in some cases

AIs (like adex or letro) block the very enzymes that convert test to estrogen, as opposed to working on the receptors, thereby reducing systemic estrogen altogether. However, the aromatase enzymes can be re-activated once the AIs get flushed out of the system, which, as the enzymes continue to accumulate, can create an estrogen rebound effect when product is discontinued.

Suicide AIs (like aromasin) are kamikaze compounds that permanently bind and deactivate the aromatase enzyme, thereby not only reducing systemic estrogen but ensuring little or no estrogen rebound occurs when you discontinue using it. Your body has to produce new aromatase enzymes to replace the lost ones, not add to it.

thanks man, finally someone replied to my post...the whole reason i posted this was b/c i was wondering how effective a SERM like nolvadex would be in helping me with an over abundance of estrogen, i would much rather be taking arimidex or letro but unfortunately my source has neither one right now so im reduced to nolva and proviron to help block my estrogen

[M302_Imola]

You can find arimidex (liquidex) at the A-R store.