
Originally Posted by
cutting_king
I actually find that if doing small doses of d-bol its better to take it all at once 1st thing on a morning. This is due to a small percentage of the drug not making it into your blood stream, therefore if you are taking 5mg every 4 hours, you may only have 3-4mg in your body throughout the day, where as you could take the full 20mg in the morning, this would mean that for a good few hours you would have 17mg or so in your system which would have more of an effect. Also because of the short half life, if you take it once a day then your natural test production is only suppressed for 4 hours (ish) and the rest of the day and night it can be recovering. Anyway this is my understanding of it and the approach i've taken in the past. I hope someone can correct me if i'm wrong
King
Although your logic is sublimely impeccable, it isn’t readily transferrable to this type of drug administration because though mathematically sound it doesn't account for a number of other variables and necessary operations/processes.
It’s like saying a cake baked for 30 mins at 400 degrees, would be just as good at 800 degrees for 15 mins. Or that 400 mgs of Ibuprofen usually starts taking effect within 30 minutes and should last at least six hours, so 2.5 grams (just over 4x that amount) should last 24hrs and kick in at 7.5 mins.
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Firstly, ester-restricted drugs are time released, so regardless of dosage you need to capitalize on this process to best manage blood concentrations (temporary levels) and to attain steady-state (accumulated permanent levels)…hence dose division and frequency. Secondly, suppression or oppression (shut down) are not temporary events, but rather LONG sustained conditions. In other words, you can't run a Dbol cycle and only be suppressed/oppressed (depending on dosage & duration) for the fraction of each day during which serum levels are highest because the negative feedback loop (NFL) simply doesn’t work that quickly. For example, the NFL's point of view would never be, "I sense a new Dbol dosage at 8am, less at noon, still less at 4pm, so I’ll start producing natty again at 5pm." It doesn't work that way!
Moral of the story: For optimal results administer drugs based on the half-life.