Yes, it makes a difference for me in maintaining my gains when I come off cycle...Yes, it seems to help keep water retention in check when I am on cycle; I now use proviron as a replacement to an AI when I am on cycle and it gets the job done for me...the synergy involved when ran in conjunction with other compounds is great too...I just love proviron...you just can't go wrong with it IMO.
I don't encounter any negative sides that I am aware of from the use of proviron...it doesn't impact my liver values and I can recover no problem during PCT and still continue to run proviron no higher than 50mg/ed...I prefer 25mg/ed by the end of PCT just to err on the safe side of caution though, but while on cycle, I'll run it as high as 100mg/ed...I find no use for any dosing higher than that. The only side I would caution anyone about is the potential for hairloss if you're prone, due to proviron being a DHT derivative.
I run 2 cycles/yr...bulk in winter, followed by cutter in spring...using proviron in between really seem to help in maintaining my gains achieved from a cycle plus it really keeps the libido up there as well, which in the past, I've found it to really take a dive when I would come off cycle, but not with the proviron.
IMO, it's a fantastic drug and by far the most under-rated AAS out there...I say if you can afford it, go for it.
Respect,