Just wanted to go back to testosterone 101. Its always good for some of us to take a refresher class so we don't get caught up in too many falsehoods about the underlying facts of what it actually is and does. I've wrote about this subject back in the day for college, but its been awhile. I understand that things herein are not sourced as they should be. Just grabbed some cut and pastes of evidence I trust is true. It seems like some "so-called-facts" or advices holding no evidence online are spreading like wildfire and are becoming a norm to everyone. Many of this concepts I've never heard to be true. Hope you enjoy,,,
The possibilities of testosterone therapy are enticing — increase your muscle mass, sharpen your memory and mental focus, boost your libido, and improve your energy level.
Your body's testosterone level peaks during adolescence and early adulthood. Starting around age 40, your body produces less testosterone. For most men, testosterone levels decline modestly. You lose about 1 percent a year -- a harmless decline in the short term, but a cause of obesity, brittle bones, muscle loss and impotence by the time you reach your 60s
Testosterone deficiency can have several effects on the body, including:
- Decreased sexual function
- Loss of bone density
- Loss of muscle mass
- Increase in fat mass
- Reduced muscle strength
- Memory loss
- Mood changes and depression
Most people know that testosterone is responsible for muscle gains and for sexual health. Testosterone is also a potent fat burner (anti-lipolytic). This is the reason why women and men with low testosterone levels have an easy time gaining fat.
Testosterone, like all androgens, leads to higher density of adrenoreceptors in the fat cells causing fat loss. Testosterone like all steroids, also helps block the cortiscosteroid receptors for the hormone cortisol. Cortisol is a hormone which promotes muscle wasting. Testosterone has many other complex actions on the body on the cellular level. It also works synergistically with other hormones in the body, such as growth hormone, to help promote fat loss. Testosterone also converts to estrogen and DHT, both of which also have anti-lipolytic properties to them.
We have used the term “fat loss” liberally. Testosterone doesn’t inherently cause fat burning, nor does any steroid for that matter. What really happens is it helps protect against fat synthesis( fat gain). Either way of looking at it, they both give the same ultimate result in the end, which is loss of fat.
Carrying excess body fat elevates your estrogen levels, and that may cause your testosterone levels to sink, says Joseph Zmuda, an epidemiologist at the University of Pittsburgh.
When you want to trim down quickly, you probably starve yourself while exercising like a madman. One of the many reasons this stops working in your 40s, when your natural testosterone levels start dropping, is pretty simple: Cutting your calorie intake by more than 15 percent makes your brain think you're starving, so it shuts down testosterone production to wait out the famine. "There's no need to reproduce if you're starving," explains Thomas Incledon of Human Performance Specialists in Plantation, Fla. Ironically, this dive in circulating testosterone stops you from burning body fat efficiently, so you're actually thwarting your hard efforts to melt that tire off your gut.
The average male produces 4-7mg of testosterone per day in a circadian pattern, with maximal plasma levels attained in early morning and minimal levels in the evening. Testoderm (scrotal) or Androderm (nonscrotal), contain natural testosterone and are typically worn for 12 or 24 hours and can be worn during exercise, bathing, and strenuous activity. It delivers about 4-6mg of testosterone daily.
Doing the math at even 7mg. a day would give you 49mgs. a week naturally high. Given that cyp and ent. is active for at least 2 weeks at 250mg./w shouldn't really be looked upon as underdosed. Thats more than 10x natural production.
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Originally Posted by 10nispro
