I searched and was surprised to find nothing on this topic.

I want to know the signs, and when you should really be worried during a cycle.

I'm at the end of week 7 and I have sore nipples, but thats it. I'm getting paranoid! They look puffy, but I'm bulking and I dont know if its directly related to the cycle.

When do you know for sure that you should consider taking some anti-e's, in my case Nolva?