has any one herd of this new steroid i herd it's over 100 times stronger then testosterone and very potent. it comes from the UK.
Productive Member
Mt-dmn
has any one herd of this new steroid i herd it's over 100 times stronger then testosterone and very potent. it comes from the UK.
Member
Lol and I thought Tren was crazy because it was 5 times stronger than Test, rofl...
Productive Member
i found a lot of info on it on another site.Originally Posted by TractionIssues
this stuff sounds good.
Anabolic Voice of Reason
Someone else may know more, but here is what I could find about it....
methyltrienolone and dimethandrolone stack-
Dimethandrolone is a porcupine anabolic steroid that exceeds the muscle building effect of testosterone by a factor of 136. In addition, dimethandrolone does not affect the prostate and the chance of estrogen side-effects is virtually nil.
Through its powerful progesterone effect, dimethandrolone suppresses the body’s own production of hormones and sperm almost entirely. Pharmacists are therefore examining whether it’s possible to put dimethandrolone into a male contraceptive. If dimethandrolone does turn out to have any serious side effects, they are likely to be linked to the recovery of the axis.
The usual concentration of dimethandrolone in the illegal drugs is 200 mg per millilitre. Injections are needed daily or every other day.
The drug also contains 3 mg of methyltrienolone per millilitre. For years methyltrienolone [aka methyltrenbolone] was the most powerful steroid ever made. But it never made it to the market because in human trials it turned out to have devastating effects on the liver. Users’ livers were not only affected very quickly, but after stopping the drug the liver continued to deteriorate.
The addition of methyltrienolone increases the risks to the liver. It’s clear that MT-DMN is an incredibly powerful stack. Health-conscious users however won’t start taking MT-DMN, but are more likely to look for a drug containing pure dimethandrolone.
Conventional doping tests don’t yet pick up dimethandrolone, but recent events in Greece show that this is no longer the case for methyltrienolone.
Post Cycle Extraordinaire~GOT PCT?
If it contains methyltrienolone, im out...
Productive Member
i tried to look it up to see if i can find a site that sells it but no luck. i do believe it is only sold in the UK.
"AR's Personal Trainer"
holy shit
Member
Lemme guess you wanna know if they make this in cyp form?
Productive Member
Dimethyl-nandrolone is 136 times stronger than testosterone.
American researchers experimented with this new nandrolone analogue that seems to possess monstrous qualities. That became clear from their publication that was published in the Bioorganic & Medicinal Chemistry Letters. The new 19-nor-androgen appears if you add a methyl group on two spots at the nandrolone-molecule. On 7alfa and on 11beta. About the adding of methyl-groups on 11beta, the researchers write:
Introduction of an 11b-methyl substituent into steroid hormones has been reported to have significant effects on biological activity.
In rabbits, 11b-methyl-17a-ethynyl- 17b-hydroxyestr-4-en-3-one has 25-fold the progestational activity of norethindrone (its 11-nor homolog). The 11b-methyl compound also has some estrogenicity (ca. 16% of estrone in rats).
11b-Methylestradiol has 124% the relative binding affinity of estradiol for the rat estrogen receptor and is equivalent to estradiol in uterotropic activity.
Baran et al. also report in a patent that 11b-methyl-19-nortestosterone has androgenic activity, although data are not given.
The designers of the new androgen started with 11beta-methylnandrolon. See the attached graphical structure. The arrow at the yellow circle in the steroid molecule is the new methyl group. If you also add a methylgroep on 7alfa, this is on the same spot where the group is also added on MENT, then you get your 7alfa,11beta-methylnandrolon. The researchers found that name however too simple, because each idiot now could understand about which molecule the “genius scientist ‘ where talking. Therefore the scientist handled the term RTI-1176-012. That makes more impression. Now that term is way too complicated to handle, and nobody can remember that. Therefore the scientist abbreviated it to -012.
We have examined the effect on androgen receptor binding and activity resulting from introduction of both 7a- and 11b-methyl groups into 19-nortestosterone, and found that the combination results in enhancement of activity together with increased separation of effects on muscle and ventral prostate.
Receptor binding affinity was determined by use of the androgen receptor from cytosol of the ventral prostate of castrated male rats.
For estrogen binding, the estrogen receptor from the uterus of 15-day-old rats was used
The outcomes were, ehm, striking. Are you ready for it?
RTI- 1176-012 had a relative binding affinity for the androgen receptor of 194 ± 24 (SE, n = 4) relative to DHT = 100, compared with 162 ± 35 (n = 3) for MENT and only 22 for the 7b,11b-dimethyl analog RTI-1176-013. Estrogen receptor binding for RTI-1176-012 was very low (0.6 ± 0.56, n = 3).
The new steroid is twice as androgenic as a DHT, appeared from the tests in the test-tube. But it gets even more beautiful when the scientists wrote about their tests with rats.
Compound RTI-1176-012 (-012) (10, 40, and 160 mug total dose, given subcutaneously in 10% ethanol in sesame oil) was compared directly with testosterone (100, 400 and 1600 mug) and 11b-methyl-19-nortestosterone (10, 40, and 160 mug) in immature (22 days) castrated male rats injected daily for 7 days for effects on the ventral prostate (VP) and seminal vesicles (SV).
Anabolic activity of -012 was also assessed. Over the dose range of 0.25–1 mg total dose in a 10 day Hershberger assay -012 showed 136-fold the activity of testosterone on levator ani (LA, muscle) weight, 37-fold activity for SV and 14-fold activity for VP.
Over a similar dose range, MENT had values of 25-fold, 8-fold and 6-fold for the three tissues
In the figure below you see the relation between the quantity of dimethyl-nandrolone and the enlargement of the prostate.
If you look to the androgenic-anabolic ratio the new means is surprisingly mild, the researchers write down. By the below passage you must well consider that the American scientists have applications in low doses in mind. It never crossed their minds that this means could perhaps fall in the hands of an other target group, that will use other quantities and thinks different about side effects.
Because of the ability of receptors to modify their conformation in response to ligands, combining two substituents that reportedly contribute to a specific biological activity may or may not enhance the response.
Thus it was gratifying that our expectation of enhanced activity upon combining 7a-methyl and 11b-methyl substituents in 19-nortestosterone led to a potent and selective compound.
In our tests, this modification resulted in at least a 5-fold increase in androgenic potency over the compound with only the 11a-methyl group when measured by the effect on VP.
The 2-fold difference observed over the 7a-methyl compound for this same endpoint was less striking, but still indicated at least equal if not increased potency.
More importantly, the increase in anabolic potency for the 7a,11b-dimethyl modification appears to be markedly greater, and the LA:VP ratio is 5-fold more than that of the selective 7a-methyl analog at similar doses, indicating a more selective anabolic:androgenic ratio for –012.
Cook CE, Kepler JA. 7a,11b-Dimethyl-19-nortestosterone: a potent and selective androgen response modulator with prostate-sparing properties. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1213-6. [Link]
"AR's Personal Trainer"
hahahaha no way bro I am trying to stay away from long esters. head hurts.Lemme guess you wanna know if they make this in cyp form?
this is company that makes it I think
http://www.hardcorelabs.org/development/index.html
Member
I would have to say just because they state it is 136 times stronger than test does not mean you will gain 136 times more mass hehe... At best it might mean an extra 5 lbs at the end of the cycle. In a way it's just the wording that makes it seems so powerful.
Anabolic Voice of Reason
Yeah, but then we have to figure the weight you will lose when your liver goes out and is removed....
Member
Lol, nice one.
"AR's Personal Trainer"
Since it is not assessed yet then it is not illegal right?
Productive Member
it is illegal. that i know of you can only get it in the UK right now.
AR's Mass Monster
I am going to sticl with good ole test! Has worked just fine for many years and I am sure it will work just fine for many to come!
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