Now i have heard that letro takes time to kick in and in order for it to kick in it has to be taken ED, is this true. Now when on a cycle (ex: Test, Deca for bulk) taking letro if you took .50mg ED wouldnt that kill your gains along with your sex drive and estrogen. could letro be taken E3D or E5D @ .50mg to keep sides away? I ask this because looking at a letro pill that is 2.5mg per pill and you cut in half you get 1.25mg which is very high dose, cut that in half you get .62mg now its so small you can't cut it anymore, how would you get .25mg?