I know it reduces protein synthesis, but what's the deal here? I am not feeling well and usually I try to refrain from taking it due to this reason. Today It's worse though so I took it this morning. Anyone have any knowledge on this subject?
I know it reduces protein synthesis, but what's the deal here? I am not feeling well and usually I try to refrain from taking it due to this reason. Today It's worse though so I took it this morning. Anyone have any knowledge on this subject?
?
if you feel ill... Take a tylenol
no need to over analyze its effects on protein syn.
If your worried about protein synth dont be. But if you take orals while on cycle try to not take tylenol. Ive seen that stuff do some horrable things to healthy people who take just a couple over the recommended dosage.
I was taking orals but I have been done with dbol for 3 and a half weeks. I am still on cycle though
Acetaminophen reduces inflammation via inhibition of PGF's (Prostaglandins) If you're not familiar with the term, to not complicate your life to much, let's put it this way:
1.- Weight training triggers the release of arachidonic acid.
2.- Arachidonic acid (the guilty one of your soreness) triggers inflamation via prostaglandins
3.- Prostaglandins are highly related to growth hormone's such as MGF (mecano growth factor) and IGF-1 (Insulin-like growth factor), then, those to HGH... And that means at high term muscle gain.
If you interrupt this whole process by taking NSAID's, forget about your training induced muscle growth AT LEAST for that day.
It depends on the dose for sure... But if you're not dying in agony of pain, why bother and sabotage your daily hard work in the gym?
Use it only when it's REALLY necessary. And if you're going to hurt your progress already, at least make it count and take something stronger. As it would be diclofenac sodium via I.M or I.V or simply hidrocodone... If you get it.
Last edited by RED26; 05-06-2010 at 12:30 PM. Reason: Grammar mistakes. Damn!
Tylenol is hard on your liver. My step dad is a doctor and said that it should not have ever been fda approved.
hmmm interesting..ive been taking aspirin everyday so far in my cycle to thin my blood(using eq) im thinking i should probably stop then if its affecting protien syntesis??? sh*ttt
If I have a headache I am taking something for it. Whats worse for gains a tylenol or missing training for a few days or shitty workouts??
Im not!!! LOL I am saying I would rather take a tylonol than miss a workout. I thought it was very clear??
BTW I would be willing to bet he is taking aspirin for the same reason I am to keep his blood from getting thick. AAS will do that to you increase red blood cel count.
Last edited by gymnerd; 05-06-2010 at 08:34 PM.
yeah i didnt use it for headaches, just to thin my blood....
i guess im gonna let it thick up, i def dont want to mess with my protien syntesis thats for sure!! no but seriously like gymnerd said is it a good idea though? ive always known to use aspirin while using compounds that increase rbc..?
RED
Read this:
Note that acetaminophen (Paracetamol; Tylenol) is not on this list. LIST OF NSAIDS. Acetaminophen belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers). The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold, that is, by requiring a greater amount of pain to develop before it is felt by a person. It reduces fever through its action on the heat-regulating center of the brain. Specifically, it tells the center to lower the body's temperature when the temperature is elevated. Acetaminophen relieves pain in mild arthritis but has no effect on the underlying inflammation, redness and swelling of the joint.
Im not going to give you a hard time. But Tylenol is hard on the liver. My wife is taking it now, she has two broken arms. The DR's told her it's hard on her liver. Tylenol does not decrease inflammation.
Last edited by Bossman; 05-07-2010 at 01:26 PM.
fu.ck so my hard workout yesterday was a waste along with the hell I go through to eat 4000 calories per day? I am seriously pissed
no. damn people exaggerate this stuff so much. May it effect protein synthesis yes. It doesn't reduce it to zero. Your workout wasnt lost and like Red said you will not build any muscle that day is BS.
If you need to take something take it. I wouldnt make it an everyday habit.
I have a buddy that playd NFL. He said the only thing locked up is the ibuprofin. I've known it inhibits muscle growth for a years now and just live with pain. Broke my knee cap and jacked liggs, previous spraind lower back, pinched nerves, tore a rotar, not to mention soarness from liften. The only time I take it is if I can't walk or have a fked up hangover, or a fever, which means I aint goin to the gym that day anyway. And if you take it more than 2 weeks ed its proposed to get a liver check at your dock. I was like what?!
Fvcking panzies.. i live off of ibuprofen, Acetaminophen, Naproxen sodium, and aspirin...
Excedrin is my Pre workout supplment!.. if my joints hurt i take ibuprofen, which is every leg day.. i take naproxen sodium when ever my lower back hurts.. thats on deadlift day.. and when i have a hard day at work (im an industrial electrician and do tons of work w/ pipe/conduit where the 10' stick can weigh 80-120lbs) running lots of pipe..
i take aspirin every morning for my heart?
SO IN SUM- I take NSAIDS almost every effin day.. and im still bigger than the majority of the people here... so either..
A).. the effects of NSAIDS is extremely over exaggerated
or
B).. if i would NOT of taken them my whole life.. i could probably be 400-500lbs of solid gradeA'Beef.. since i would be like 2x as big as i am now
x3 well said.
this is one of those stupid misconceptions that ALWAYS gets completely blown out of the proportion. If you're currently in an anabolic state you won't see any decrease in gains from taking NSAIDS. your on steroids.... WTF would you be worried about muscle wasting now. LOL.
I'd understand if you were more concerned about taking ibuprofen during PCT or post cycle. but yah... nothing to worry about OP. you're over thinking this IMO.
-VM
No joke. My mother almost ODed from Vicodin when my parents were splitting up (very rough times - still no excuse shes a pill popper) because its made up of codeine and tylenol, which is very harsh on your liver. Docs said if she would've taken a few more, chances are her liver might have gone out.
Dont underestimate it just because its an OTC med.
x2
There are PLENTY of people who even mix methadone w/ AAS usage, and still are huge. (not saying it's particularly smart, just saying...)
Don't even get me started on bodybuilders and hypnotic usage. LOLL. (I've gotta get out of this thread before I start to write an essay, HA)..
-VM
LOL, I was a regular with NSAIDS until I got ulcerative colitis (taking them had nothing to do with me getting UC). Now I take celebrex. I still take ibuprofen, aspirin and even tylenol if the pain is bad enough. Pain raises cortisol which can cause more problems then the minor issues with NSAIDS. Better to treat the pain. Bodybuilding/powerlifting...hurts.
NSAIDs may have some inhibiting factor to protein synthesis but to say it negates any gains from a workout the day you take it is utter bullshit. Complete nonsense.
Like taiboxa, I live on NSAIDs and anti-inflammatories. I take 2000mg of Relafen every freakin day for osteoarthritis issues, and often take a couple of doses of Tylenol during days when I'm on my feet a lot because the knees hurt so bad. It's the lesser of two (or three) evils for me. I'm on an elevated TRT dose right now while running deca and my gains have been pretty outstanding. I'd rather be in less pain throughout the day so I can enjoy life to the fullest extent than worry about the minor impact NSAIDs are going to have on my gains.
FYI, for those of us with UC/chron's or other stomach issues (I know there are some of us out there) google "ibugel". It's not available in the US but you can get it without a prescription from other countries. It's a transdermal ibuprofen. I went through tubes of this stuff this past winter when bulking. Stuff is great! Get the 10mg dose. 5mg is too weak IMO.
so would guys say to continue using aspirin on cycle to thin blood or not use it? thanks
There are currently 1 users browsing this thread. (0 members and 1 guests)