Bioidentical Pellets or Synthetic Test? What's your take?

[WallyWorld637]

I have been away from TRT for a few years and I can tell a difference in my life (for the bad). If your wondering why, bad experience with my doc... Long story, plus i was having huge problems pinning myself. Anyway, now that I'm wanting to get back to it I'm noticing docs pushing the bioidentical pellets because it's suppose to be identically the same as test that's made by the body. Everyone I have called say that synthetic test has a higher risk of you getting cancer.

Anyone have any input on this?

[zaggahamma]

face your fear my brother

[WallyWorld637]

LOL your right. I think it comes down to get educated by a professional on pinning myself. I'm gonna do this.

[zaggahamma]

i'm glad to hear u say that bro...i'm glad i helped..i hope you get the best out of your trt

[GotNoBlueMilk]

You can pin subq too. Uses insuline needles and is painless. Can't comment on how IM feels since I have never done it.

Pellets are an option, just cost more. I react a little to the cotton oil in Test Cyp, so I wouldn't mind pellets at all if I could get past the dosing issue. Hard to adjust once you have them in there.

[OutLaw8.5]

SOrry to hijack,

GOTNO. Any more readin info on subq test injection... DOing most stuff from my phone and I don't think it google searches the same or the way I'm searching isn't very good. All the information I'm finding is very dated

Thanks

8.5

[Dragon666]

Subq test esters? Hmm... any reason you choose this over Intra M?

[PPC]

Injected test is bio identical. Synthetic test used to be given orally in the 50's and yes there were complications with the liver etc...it was methyltestosterone. But now that is not standard T therapy, it's highly unlikely an oral form would be prescribed. No matter the form these days...test is test. T cyp will not cause a greater incidence of cancer. T cyp is just attached to the oil and the body separates the two after injection so once the separation occurs you are left with bio identical testosterone just like your own body makes.

But pellets work for some. My brother has pellets and feels great. Some people say there is less risk of cancer with pellets because they are less likely to raise E2 and DHT. If one believes DHT can cause prostate cancer then that is where the connection is being made. I don't think DHT causes cancer...it may fuel whatever is already there but even that is up for debate.

[OutLaw8.5]

Why are pellets less likely to convert to e?

[GotNoBlueMilk]

The reduction in E2 conversion of pellets is minimal. YOu never have the spikes you get from injecting T once every 2 weeks, or even once every week. Because the spike is less you have less conversion. But if you are injecting twice a week then you get a minimal spike anyway so the difference with pellets is hardly worth considering.

[OutLaw8.5]

I'm still working on doctors to get to inject myself because I'd split my 100 up twice a week


Any good reading on subq test?

[GotNoBlueMilk]

This is the most popular, as well as the first, study done:

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1: Saudi Med J. 2006 Dec;27(12):1843-6.Links
Subcutaneous administration of testosterone. A pilot study report.
Al-Futaisi AM, Al-Zakwani IS, Almahrezi AM, Morris D.

Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman. [email protected]

OBJECTIVE: To investigate the effect of low doses of subcutaneous testosterone in hypogonadal men since the intramuscular route, which is the most widely used form of testosterone replacement therapy, is inconvenient to many patients. METHODS: All men with primary and secondary hypogonadism attending the reproductive endocrine clinic at Royal Victoria Hospital, Monteral, Quebec, Canada, were invited to participate in the study. Subjects were enrolled from January 2002 till December 2002. Patients were asked to self-administer weekly low doses of testosterone enanthate using 0.5 ml insulin syringe. RESULTS: A total of 22 patients were enrolled in the study. The mean trough was 14.48 +/- 3.14 nmol/L and peak total testosterone was 21.65 +/- 7.32 nmol/L. For the free testosterone the average trough was 59.94 +/- 20.60 pmol/L and the peak was 85.17 +/- 32.88 pmol/L. All of the patients delivered testosterone with ease and no local reactions were reported. CONCLUSION: Therapy with weekly subcutaneous testosterone produced serum levels that were within the normal range in 100% of patients for both peak and trough levels. This is the first report, which demonstrated the efficacy of delivering weekly testosterone using this cheap, safe, and less painful subcutaneous route

[GotNoBlueMilk]

Keep in mind that pellets are subq and in the glute/hip region where there is lots of fat! So the whole E2 conversion arguement against subq injections is pretty worthless.

[OutLaw8.5]

Thank you sir

[Dragon666]

I don't find the intramuscular injections hurt much at all. But I'll keep an open mind regarding the subq technique. Scar tissue is my only complaint regarding intramuscular injects.

Whereabouts do you choose to do your subq injects? Stomach/hip/glut? And how much we talking here? .5 ml - 1.0 ml I might assume.

[GotNoBlueMilk]

I do the thighs. I don't have much fat on the thighs, it's easy to reach, and I can sit on my butt while I inject.